Results 61 to 70 of about 280,153 (251)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Marketing Research of the Medical Institution in the System of Voluntary Medical Insurance for Making Managerial Decisions

Вестник Российского экономического университета имени Г. В. Плеханова, 2018
The segment of voluntary medical insurance is a promising type of insurance. This situation encourages insurers to develop advanced competitive products with continuously upgrading level of service.
A. B. Tsvetkova, R. Kh. Yunisov
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

An Early Medical Illustration of Paroxysmal Dystonic Phenomena. [PDF]

Mov Disord Clin Pract, 2022
Brigo F, Trinka E, Study Group on the History of Neurology of the Italian Neurological Society†.   +2 more
europepmc   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

On the change of information technology in the field of Medical Biometry and Statistics

GMS Medizinische Informatik, Biometrie und Epidemiologie, 2005
An overview on the applications of information technology (IT) in Medical Biometry and Statistics is given using the developments at the Department of Medical Biometry and Statistics in Freiburg for illustration.
Roßner, Reinhard
doaj  

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Is dermatological lilac really lilac?

Dermatologica Sinica, 2018
Background/Objective: Dermatologists use the word lilac to describe a shade of erythema; especially in lichen planus, morphea, and dermatomyositis. The aim of this study to determine whether or not there is a color really consistent with a lilac color ...
Bilge Fettahlıoğlu Karaman, Suhan Gunasti Topal, Aydin Yucel, Varol Lutfu Aksungur   +3 more
doaj   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

A Monte-Carlo planning strategy for medical follow-up optimization: Illustration on multiple myeloma data.

PLoS ONE
Designing patient-specific follow-up strategies is key to personalized cancer care. Tools to assist doctors in treatment decisions and scheduling follow-ups based on patient preferences and medical data would be highly beneficial.
Benoîte de Saporta, Aymar Thierry d'Argenlieu, Régis Sabbadin, Alice Cleynen   +3 more
doaj   +1 more source