Results 141 to 150 of about 18,046,440 (303)
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Uncertainty Quantification in Medical Image Segmentation: A Comprehensive Survey. [PDF]
Ziaee SS, Ovens K.
europepmc +1 more source
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Deep learning for medical image analysis /
"Deep learning is providing exciting solutions for medical image analysis problems and is seen as a key method for future applications. This book gives a clear understanding of the principles and methods of neural network and deep learning concepts ...
Zhou, S. Kevin,editor. +2 more
core
Selective Confidence-Guided Projection-Based Encoding for Medical Image Classification. [PDF]
Chen T +4 more
europepmc +1 more source
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
WVM-UNet: A Wavelet-Vision Mamba Framework for Enhanced Medical Image Segmentation. [PDF]
Yang Y, Gao W, Wu Z, Yang C.
europepmc +1 more source
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
TransCat: a hybrid CNN-transformer network with KAN for medical image segmentation. [PDF]
Wang J +5 more
europepmc +1 more source

