Results 171 to 180 of about 1,481,089 (317)

Southwest view of Medical College quadrangle

open access: yes
This glass lantern slide features a ground view of the southwest side of the Medical College of South Carolina ...
Medical College of South Carolina (1952-1969). Department of Medical Illustration
core  

An effective deep learning algorithm for medical image registration. [PDF]

open access: yesPLOS Digit Health
Deng J   +5 more
europepmc   +1 more source

Medical College Hospital construction, view from Doughty Street, 1953

open access: yes, 1953
This glass lantern slide features a ground view of a color photograph of the construction site for the Medical College of South Carolina Hospital, facing Doughty Street, in ...
Medical College of South Carolina (1952-1969). Department of Medical Illustration
core  

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

Medical College of South Carolina marsh site for housing, 1952

open access: yes, 1952
This glass lantern slide features an aerial camera view of a color photograph of a marsh site for housing construction for the Medical College of South Carolina in ...
Medical College of South Carolina (1952-1969). Department of Medical Illustration
core  

Foundation Models Meet Medical Image Interpretation. [PDF]

open access: yesResearch (Wash D C)
Jiao L   +11 more
europepmc   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

open access: yesMolecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi   +14 more
wiley   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

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