Results 41 to 50 of about 1,363,601 (269)
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Applied Sciences, 2020 Malignant lesions are a huge threat to human health and have a high mortality rate. Locating the contour of organs is a preparation step, and it helps doctors diagnose correctly.
Chen Li, Wei Chen, Yusong Tan
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Deep Learning Applications in Medical Image Processing
Acta Infologica, 2021 Medical imaging techniques such as magnetic resonance imaging (MRI), computed tomography (CT), positron emission tomography (PET), mammography, ultrasound and x-ray have been used for the diagnosis and treatment of diseases for many years.
Ayşe Gül Eker, Nevcihan Duru
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Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
A New Deep-Learning-Based Model for Breast Cancer Diagnosis from Medical Images
Diagnostics, 2023 Breast cancer is one of the most prevalent cancers among women worldwide, and early detection of the disease can be lifesaving. Detecting breast cancer early allows for treatment to begin faster, increasing the chances of a successful outcome.
Salman Zakareya +2 more
doaj +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
European Radiology ExperimentalObjective Primary sclerosing cholangitis (PSC) is a rare fibroinflammatory hepatobiliary disease with a highly variable clinical course. Identifying patients at risk for poor outcomes remains challenging. Magnetic resonance imaging (MRI)-based approaches
Wolf C. Bartholomä +7 more
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FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Scientific ReportsMedical Object Detection (MOD) is a clinically relevant image processing method that locates structures of interest in radiological image data at object-level using bounding boxes.
Gabriel Rashidi +5 more
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