Results 81 to 90 of about 17,816,512 (303)

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Relevance feedback and intelligent technologies in content-based image retrieval system for medical applications [PDF]

, 2004
Relevance feedback has gained much interest from researchers in the discipline of content-based image retrieval (CBIR). However, such approach is rarely used in the content-based medical image retrieval (CBMIR) systems.
Fung, C.C., Chung, K.P.
core  

Social Accountability of Medical Schools: Concept and Implementation [PDF]

, 2019
Medical schools have been working to produce competent doctors and improve the quality of care by introducing and implementing new curricula and innovative teaching and learning methods.
Korean Medical Education Review (의학교육논단)
core   +1 more source

A Novel Artificial-Intelligence-Based Approach for Automatic Assessment of Retinal Disease Images Using Multi-View Deep-Broad Learning Network

IEEE Access
Retinal disease detection and diagnosis relying solely on artificial retinal diseases will put great pressure on doctors and increase the rate of misdiagnosis.
Ao Zhang, Xin Qian, Chengcheng Xu, Jie Zhang   +3 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Measuring CSF net velocity in the human subarachnoid space with 7T MRI: testing the classical view of CSF absorption

Fluids and Barriers of the CNS
Traditionally, cerebrospinal fluid (CSF) is believed to exit the brain via arachnoid villi, being absorbed into the superior sagittal sinus (SSS), with a net flow towards these exit sites driven by constant CSF turnover.
E. C. van der Voort, M. C. E. van der Plas, M. W. J. M. Gosselink, J. J. M. Zwanenburg   +3 more
doaj   +1 more source

3D Vessel Centerline Extraction via Vascular Morphology Driven Adaptive Deep Reinforcement Tracking

IEEE Access
Accurate vessel centerline extraction in medical images has important clinical value for preoperative diagnosis and intraoperative intervention of vascular diseases.
Jingliang Zhao
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Secure Medical Image Sharing: Technologies, Watermarking Insights, and Open Issues

IEEE Access
With the growth of the Internet, medical documents have become widely used by healthcare professionals. Secure transmission and management of medical images are essential to enable collaboration while protecting sensitive patient information.
Sawsan D. Mahmood, Fadoua Drira, Hussain Falih Mahdi, Adel M. Alimi   +3 more
doaj   +1 more source