Results 111 to 120 of about 17,816,512 (303)

A Combined Loss-driven Framework for Automated Parotid Segmentation in Head-and-Neck Computed Tomography

Journal of Medical Physics
Purpose: This study presents a deep learning framework for automatic parotid segmentation using three-dimensional (3D) U-Net and attention-augmented 3D U-Net architectures trained with a novel combined loss function tailored for anatomical accuracy and ...
Aryan Tyagi, Anuj Kumar, Sandeep Singh, Mohini Manav, Soniya Pal   +4 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Medical College court, 1950

, 1950
This glass lantern slide features an aerial view of the Medical College of the State of South Carolina court in ...
Medical College of South Carolina (1952-1969). Department of Medical Illustration
core  

Automated Computer-Assisted Diagnosis of Pleural Effusion in Chest X-Rays via Deep Learning

Diagnostics
Background/Objectives: Pleural effusion is a common pulmonary condition that, if left untreated, may lead to respiratory distress and severe complications.
Ya-Yun Huang, Yu-Ching Lin, Sung-Hsin Tsai, Tsun-Kuang Chi, Tsung-Yi Chen, Shih-Wei Chung, Kuo-Chen Li, Wei-Chen Tu, Patricia Angela R. Abu, Chih-Cheng Chen   +9 more
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Medical Center campus, 1953

, 1953
This glass lantern slide features a map of the Medical Colleg of South Carolina Medical Center campus in ...
Medical College of South Carolina (1952-1969). Department of Medical Illustration
core  

Early Diagnosis of Blood Disorders via Enhanced Image Preprocessing and Deep Learning Modeling

BioMedInformatics
Background: Accurate and early detection of hematological disorders from microscopic peripheral blood smear images remains a technically challenging task due to inherent imaging limitations, including noise contamination, low contrast, staining ...
Alpamis Kutlimuratov, Dilshod Eshmurodov, Fotima Tulaganova, Akhmet Utegenov, Piratdin Allayarov, Jamshid Khamzaev, Islambek Saymanov, Fazliddin Makhmudov   +7 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Medical Center, 1950

, 1950
This glass lantern slide features an aerial view of the Medical Center building of the Medical College of the State of South Carolina in ...
Medical College of South Carolina (1952-1969). Department of Medical Illustration
core