Results 91 to 100 of about 2,936,368 (282)

P396: DYSREGULATED DNAM-1 AND KIR2DL1 EXPRESSION IN NATURAL KILLER CELLS CORRELATES WITH POOR OUTCOME IN ACUTE MYELOID LEUKEMIA

HemaSphere, 2022
A. F O Costa, L. O Marani, I. A Lopes, L. S Binelli, P. S Scheucher, J. L S Schiavinato, M. I. A Madeira, K. B B Pagnano, B. K Duarte, A. B. F Glória, E. M Rego, F. Traina, R. Welner, L. L Figueiredo-Pontes   +13 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

LUneXt: Simple and Efficient U-shaped Network Design for Medical Image Segmentation with Nonlinear Activation

Computing Open
Medical image segmentation has always been a challenging task. This paper proposes a new LUneXt medical image segmentation model based on the characteristics analysis of medical image data sets and testing of different nonlinear activation units.
Guanghong Deng, Bing Yu, Wenlong Jing, Yong Li, Xiaodan Zhao   +4 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Improving Computer-Aided Medical Diagnosis Using Generative Adversarial Networks for Carotid Artery Ultrasound Image Data Augmentation and Classification

Journal of Electrical Engineering and Computer
Cardiovascular diseases are a leading cause of death globally, making early detection of atherosclerosis critical for prevention. Carotid artery ultrasound imaging is a common diagnostic tool; however, the limited availability of labelled medical images ...
Ricardo Fitas, João Gonçalves
doaj   +1 more source

MIRACLE’s Naive Approach to Medical Images Annotation

, 2005
One of the proposed tasks of the ImageCLEF 2005 campaign has been an Automatic Annotation Task. The objective is to provide the classification of a given set of 1,000 previously unseen medical (radiological) images according to 57 predefined categories ...
González Cristóbal, José Carlos, Goñi Menoyo, José Miguel, Martínez Fernández, José Luis, Villena Román, Julio   +3 more
core  

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Recurrent Gynecological Tumors in Previously Irradiated Patients. Does Re-Irradiation with Stereotactic Body Radiotherapy Have a Role? A Systematic Review

Clinical and Experimental Obstetrics & Gynecology, 2023
Antonio Pontoriero, Paola Critelli, Alberto Bosurgi, Chiara Carrubba, Corrado Spatola, Giacomo Ferrantelli, Federico Chillari, Valentina Zagardo, Anna Brogna, Gianluca Ferini, Silvana Parisi, Stefano Pergolizzi   +11 more
doaj   +1 more source

Medical Imaging Informatics [PDF]

Yearbook of Medical Informatics, 2002
C A, Kulikowski, R, Haux
openaire   +2 more sources

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source