Results 131 to 140 of about 1,754,104 (286)
Medical image of the week: Bochdalek hernia [PDF]
, 2016 Muna Omar, Linda A. Snyder
openalex +1 more source
Transfer Learning with Feature Extraction Modules for Improved Classifier Performance on Medical Image Data [PDF]
, 2022 Ritesh Jha +2 more
openalex +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Editorial: Editor’s challenge in medical physics and imaging: quantitative medical imaging
Frontiers in PhysicsT. Beyer, E. V. Moser
doaj +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Towards a Repository for Standardized Medical Image and Signal Case Data Annotated with Ground Truth
, 2011 Thomas M. Deserno +2 more
openalex +2 more sources
Medical image of the week: mediastinal lipomasosis [PDF]
, 2018 B Borg, James Knepler
openalex +1 more source
Development of Static and Dynamic Colorimetric Analysis Techniques Using Image Sensors and Novel Image Processing Software for Chemical, Biological and Medical Applications [PDF]
, 2023 Woo Sik Yoo +3 more
openalex +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source