Results 191 to 200 of about 2,772,177 (283)

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Evaluating Explainability: A Framework for Systematic Assessment of Explainable AI Features in Medical Imaging. [PDF]

Bioengineering (Basel)
Lago MA, Zamzmi G, Eich B, Delfino JG.
europepmc   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Artificial intelligence in medical imaging

iRADIOLOGY
Bin Huang, Bo Gao
doaj   +1 more source

Efficiency of Artificial Intelligence in Three-Dimensional Reconstruction of Medical Imaging. [PDF]

Cureus
Nikhita, Bannur D, Cerdas MG, Saeed AZ, Imam B, Thandi RS, C AH, Reddy P, Ali R.   +8 more
europepmc   +1 more source

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

FEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi, Shunsuke Morioka, Keiko Morisawa, Kazutsugu Matsukawa, Shingo Ashida, Takeshi Suzuki, Shuji Sakamoto   +6 more
wiley   +1 more source

Prostate Cancer Radiomic Features: Limited Cross-Scanner Reproducibility Despite High Reader Reliability

International Journal of Clinical Practice
Guanming Zeng, Xiangde Min, Zelin Xu, Subati Maimaitizunong, Weiyu Fan, Fei Qiao, Yan Nan, Ping Chen, Zipeng Chen, Xi Yin   +9 more
doaj   +1 more source

Phantom studies in medical imaging (PSMI): a guide with recommendations and checklist. [PDF]

Eur Radiol Exp
Gennaro G, Zanardo M, Ambrogi F, Sardanelli F.   +3 more
europepmc   +1 more source

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

FEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen, Jia‐Ci Jhang, Chun‐Yi Peng, Quốc Cường Nguyễn, Feng‐Huei Lin, Hung‐Ming Wu, Shankung Lin   +6 more
wiley   +1 more source

Artificial Intelligence Integrated Smart Medical Imaging Lab Framework for Enhanced Diagnosis and Treatment of Pandemic-Prone Diseases. [PDF]

Health Sci Rep
Tungal A, Singh P, Singh K, Kaur PD, Bharany S, Pant R, Kumar A, Rehman AU, Hussen S.   +8 more
europepmc   +1 more source