Results 141 to 150 of about 35,047 (260)
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Field Actions Science Reports, 2012 Introduction: In recent years, a number of African countries, including Niger, have adopted policies abolishing user fees at point of service, targeting categories of people or services.
Mamoudou Barro +4 more
doaj
Catastrophic Health Expenditure and Household Well-Being [PDF]
According to the catastrophic health expenditure methodology a house-hold is in catastrophe if its health out-of-pocket budget share exceeds a critical threshold.
Karine Lamiraud, Ramses H. Abul Naga
core
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Approaches to Optimize and Innovate the Policies of Poverty-relief Medical Insurance Mechanism for Impoverished Population -- A Case Study of Hebei Province [PDF]
Proceedings of the 2018 4th International Conference on Social Science and Higher Education (ICSSHE 2018), 2018 Jinguo Ye, Haifang Feng
openaire +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
The Distributional Impact of Healthcare Financing in Nigeria: A Case Study of Enugu State [PDF]
The deregulation of healthcare financing and supply in Nigeria has shifted the healthcare system towards competitive market ideals. Households' decision to utilize healthcare is identical with healthcare financing.
Hyacinth Ementa Ichoku +1 more
core +1 more source
412 Geographic and Treatment Analysis of Emerging Adult Asthmatic Patients Utilizing the City Emergency Medical Services System in a Large Impoverished Urban Area [PDF]
Annals of Emergency Medicine, 2017 E. Olsen +7 more
openaire +1 more source