Results 81 to 90 of about 35,047 (260)

Gendering Reconstruction: Iraqi Women between Dictatorship, Wars, Sanctions and Occupation [PDF]

open access: yes, 2005
The article explores the role of women and changing gender relations in reconstruction processes in Iraq. It will provide a historical background in terms of changing women’s status and gender ideologies & relations during the regime of Saddam Hussein. I
Al-Ali, Nadje
core   +2 more sources

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

The Postoperative Morbidity Survey was validated and used to describe morbidity after major surgery.

open access: yes, 2007
OBJECTIVES: To describe the reliability and validity of the Postoperative Morbidity Survey (POMS). To describe the level and pattern of short-term postoperative morbidity after major elective surgery using the POMS.
Browne, JP   +9 more
core   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Forced Migration, The Human Face of a Health Crisis [PDF]

open access: yes, 2015
Nearly 60 million refugees, asylum-seekers and internally displaced persons (IDPs) fled their homes in 2014, predominately from war-torn Syria, Afghanistan and Somalia. The global response to assisting this vulnerable group has been wholly incommensurate
Gostin, Lawrence O., Roberts, Anna E.
core   +2 more sources

From ‘Invisible Problem’ to Global Priority: The Inclusion of Mental Health in the Sustainable Development Goals [PDF]

open access: yes, 2018
Perceptions regarding the importance of mental health are shifting at a global level. Once described as an ‘invisible problem’ in international development, mental health is now being framed as one of the most pressing development issues of our time ...
Mills, C.
core   +2 more sources

Additional file 1: of Assessing the burden of medical impoverishment by cause: a systematic breakdown by disease in Ethiopia

open access: yes, 2016
1. Inputs and methods for the estimation of the burden of impoverishment due to out-of-pocket direct medical costs. 2. Sensitivity analyses. (PDF 759Â kb)
StĂŠphane Verguet   +2 more
openaire   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Medical Impoverishment And Vaccines [PDF]

open access: yesHealth Affairs, 2018
Angela Y, Chang, Stéphane, Verguet
openaire   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

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