Results 91 to 100 of about 560,065 (339)

Using philosophy to improve the coherence and interoperability of applications ontologies: A field report on the collaboration of IFOMIS and L&C [PDF]

, 2004
The collaboration of Language and Computing nv (L&C) and the Institute for Formal Ontology and Medical Information Science (IFOMIS) is guided by the hypothesis that quality constraints on ontologies for software ap-plication purposes closely parallel the
Fielding, James Matthew, Simon, Jonathan, Smith, Barry   +2 more
core  

Stereotyped Subclones Revealed by High‐Density Single‐Cell Lineage Tracing Support Robust Development

Advanced Science, EarlyView.
Based on a well‐established in vitro directed differentiation model and an integrated analysis of high‐density cell lineage trees (CLTs) and single‐cell transcriptomes, it is demonstrated that many subclones are formed by sub‐CLTs resembling each other in terms of both cell type compositions and topological structures.
Xiaoyu Zhang, Zizhang Li, Jingyu Chen, Wenjing Yang, Xingxing He, Peng Wu, Feng Chen, Ziwei Zhou, Chenze Ren, Yuyan Shan, Xiewen Wen, Vassily A. Lyubetsky, Leonid Yu. Rusin, Xiaoshu Chen, Jian‐Rong Yang   +14 more
wiley   +1 more source

CRCFound: A Colorectal Cancer CT Image Foundation Model Based on Self‐Supervised Learning

Advanced Science, EarlyView.
CRCFound is a self‐supervised learning‐based CT image foundation model for colorectal cancer (CRC). Pretrained on 5137 unlabeled CRC CT images, it learns universal feature representations, enabling efficient adaptation to various clinical tasks. The model demonstrates outstanding performance and generalization across multiple diagnostic and prognosis ...
Jing Yang, Du Cai, Junwei Liu, Zhenfeng Zhuang, Yibin Zhao, Feng‐ao Wang, Chenghang Li, Chuling Hu, Baowen Gai, Yiping Chen, Yixue Li, Liansheng Wang, Feng Gao, Xiaojian Wu   +13 more
wiley   +1 more source

Medical Informatics as a Concept and Field-Based Medical Informatics Research: The Case of Turkey

Düzce Tıp Fakültesi Dergisi
Aim: This study aimed to evaluate the position of Turkey in the field of Medical Informatics and assess the general structure of research by analyzing Medical Informatics research with bibliometric methods.
Fatih Safa Erenay, Jiban K. Pal, Ali Emre Çetinkol, İbrahim Yüksel, Tuncay Küme, Muhammet Damar   +5 more
doaj   +1 more source

LRRC8A Regulates Outer Hair Cell Volume and Electromotility and is Required for Hearing

Advanced Science, EarlyView.
This study identifies LRRC8A‐dependent volume‐regulated anion channels (VRACs) as essential for cochlear outer hair cells' electromotility and auditory signal amplification. LRRC8A deficiency disrupts cell volume control, impairs auditory sensitivity, and causes deafness, while targeted LRRC8A re‐expression restores auditory function.
Shengnan Wang, Yuehui Xi, Qiaojun Fang, Sai Shi, Fei Wang, Fuyu Xian, Zhongyang Zhang, Yuxin Yang, Xishuo Jin, Xiaomin Wang, Chen Cao, Hailin Zhang, Nikita Gamper, Zhigang Xu, Haitao Shen, Ping Lv   +15 more
wiley   +1 more source

Health and medical informatics in Croatia [PDF]

Health Information & Libraries Journal, 2008
Many failures in the health care sector are the result of not having the right information at the right time, owing to a lack of technology or knowledge of how to use it. Although there are many differences between countries, the challenge is to identify common problems faced by both big and small countries, and to search for solutions for managing ...
openaire   +5 more sources

Heterointerface‐Modulated Synthetic Synapses Exhibiting Complex Multiscale Plasticity

Advanced Science, EarlyView.
An asymmetric dual‐gate heterointerface‐regulated artificial synapse (HRAS) is developed, employing distinct ion concentrations and dielectric coupling to form precise dual‐interface channels. Through lateral modulation, HRAS realizes, for the first time, the intricate interplay of lateral inhibition/enhancement and multi‐level short‐ and long‐term ...
Xingji Liu, Yao Ni, Zujun Wang, Sunfu Wei, Xiao′en Chen, Jingjie Lin, Lu Liu, Boyang Yu, Yue Yu, Dengyun Lei, Yayi Chen, Jianfeng Zhang, Jing Qi, Wei Zhong, Yuan Liu   +14 more
wiley   +1 more source

SYMBIOmatics: Synergies in Medical Informatics and Bioinformatics – exploring current scientific literature for emerging topics

BMC Bioinformatics, 2007
Background The SYMBIOmatics Specific Support Action (SSA) is "an information gathering and dissemination activity" that seeks "to identify synergies between the bioinformatics and the medical informatics" domain to improve collaborative progress between ...
Rebholz-Schuhman Dietrich, Cameron Graham, Clark Dominic, van Mulligen Erik, Coatrieux Jean-Louis, Del Hoyo Barbolla Eva, Martin-Sanchez Fernando, Milanesi Luciano, Porro Ivan, Beltrame Francesco, Tollis Ioannis, Van der Lei Johan   +11 more
doaj   +1 more source

Development of a Taxonomy for Health Information Technology [PDF]

, 2007
Taxonomies provide schemas to help classify entities and define the relationships between them. Early computing enabled the development of ontologies and Medical Subject Headings (MeSH), the first modern classification of medical terminology as applied ...
Dixon, Brian E., McGowan, Julie J, Zafar, Atif   +2 more
core  

Gastrula‐Premarked Posterior Enhancer Primes Posterior Tissue Development Through Cross‐Talk with TGF‐β Signaling Pathway

Advanced Science, EarlyView.
A gastrula‐premarked enhancer within the first intron of Cdx2 governs posterior embryonic development via both regulating Cdx2 expression in cis and coordinating TGF‐β signaling in trans to ensure proper posterior body development. Functional rescue in gastruloids reveals a Cdx2‐independent pathway, highlighting p‐Enh‐eRNA as key epigenetic ...
Yingying Chen, Fengxiang Tan, Qing Fang, Lin Zhang, Jiaoyang Liao, Penglei Shen, Yun Qian, Mingzhu Wen, Rui Song, Yonggao Fu, He Jax Xu, Ran Wang, Cheng Li, Zhen Shao, Jinsong Li, Naihe Jing, Xianfa Yang   +16 more
wiley   +1 more source