Results 91 to 100 of about 552,595 (324)

Interleukin 6/gp130 axis promotes neural invasion in pancreatic cancer

Cancer Medicine, Volume 11, Issue 24, Page 5001-5012, December 2022., 2022
Nerve invasion (N‐inv) is an important prognostic factor in pancreatic ductal adenocarcinoma (PDAC). To elucidate circulating stimulators for nerve invasion, the authors evaluated the stimulant activity and the inhibitory effects of IL‐6/gp130 axis. Biological activity of IL‐6/gp130 axis promoted nerve invasion in murine model and was upregulated in ...
Hidetaka Suzuki, Shuichi Mitsunaga, Masafumi Ikeda, Takao Aoyama, Kazumi Yoshizawa, Masayuki Yamaguchi, Masami Suzuki, Minoru Narita, Toshikatsu Kawasaki, Atsushi Ochiai   +9 more
wiley   +1 more source

Welche Kompetenzen in Medizininformatik benötigen Ärztinnen und Ärzte? Update des Lernzielkatalogs für Studierende der Humanmedizin

GMS Medizinische Informatik, Biometrie und Epidemiologie, 2020
The digital transformation has influenced medical pathways in clinical routine and research as never before. This transformation requires multiple competencies in digital health from health professionals.
Varghese, Julian, Röhrig, Rainer, Dugas, Martin, GMDS-Arbeitsgruppe „MI-Lehre in der Medizin“   +3 more
doaj   +1 more source

2016 Year-in-Review of Clinical and Consumer Informatics: Analysis and Visualization of Keywords and Topics [PDF]

Healthcare Informatics Research, 2017
ObjectivesThe objective of this study was to review and visualize the medical informatics field over the previous 12 months according to the frequencies of keywords and topics in papers published in the top four journals in the field and in Healthcare ...
Hyeoun-Ae Park, Joo Yun Lee, Jeongah On, Ji Hyun Lee, Hyesil Jung, Seul Ki Park   +5 more
doaj   +1 more source

Does Informatics enable or inhibit the delivery of patient-centred, coordinated, and quality-assured care: a Delphi study. A contribution of the Imia Primary Health Care Informatics Working Group [PDF]

, 2015
Background: Primary care delivers patient-centred and coordinated care, which should be quality-assured. Much of family practice now routinely uses computerised medical record (CMR) systems, these systems being linked at varying levels to laboratories ...
Correa, A, de Lusignan, S, Kuziemsky, C, Liaw, S-T, Liyanage, H, Terry, Al   +5 more
core   +2 more sources

Immunity Debt for Seasonal Influenza After the COVID‐19 Pandemic and as a Result of Nonpharmaceutical Interventions: An Ecological Analysis and Cohort Study

Advanced Science, EarlyView.
This study provides support for the immunity debt hypothesis, revealing a 131.72% increase in influenza rates during winter and a 161.23% rise in summer, 1 year following the global easing of COVID‐19 restrictions. This study offers empirical evidence of immunity debt on a global level, highlighting the importance of incorporating this concept into the
Li Chen, Yuchen Guo, Kim López‐Güell, Jun Ma, Yanhui Dong, Junqing Xie, Daniel Prieto Alhambra   +6 more
wiley   +1 more source

The Expert Survey-Based Global Ranking of Management- and Clinical-Centered Health Informatics and IT Journals [PDF]

, 2015
The goal of this study is to develop an expert survey-based journal ranking for the Health Informatics & Information Technology (HIIT) field. Journal of the American Medical Informatics Association and Journal of Medical Internet Research were ranked as ...
Dohan, Michael S., Serenko, Alexander, Tan, Joseph, PhD   +2 more
core   +2 more sources

The Super Enhancer‐Driven Long Noncoding RNA PRKCQ‐AS1 Promotes Neuroblastoma Tumorigenesis by Interacting With MSI2 Protein and Is Targetable by Small Molecule Compounds

Advanced Science, EarlyView.
PRKCQ‐AS1 is overexpressed due to transcriptional super‐enhancers. PRKCQ‐AS1 RNA forms a complex with MSI2 protein to induce BMX mRNA stabilization and overexpression, ERK protein phosphorylation and neuroblastoma cell proliferation. Compound NSC617570 blocks PRKCQ‐AS1 binding to MSI2, leading to BMX mRNA disassociation from MSI2 protein, BMX reduction,
Sujanna Mondal, Pei Y. Liu, Janith Seneviratne, Antoine De Weck, Pooja Venkat, Chelsea Mayoh, Jing Wu, Jesper Maag, Jingwei Chen, Matthew Wong, Nenad Bartonicek, Poh Khoo, Lei Jin, Louise E. Ludlow, David S. Ziegler, Toby Trahair, Pieter Mestdagh, Belamy B. Cheung, Jinyan Li, Marcel E. Dinger, Ian Street, Xu D. Zhang, Glenn M. Marshall, Tao Liu   +23 more
wiley   +1 more source

The 13 th world congress on medical and health informatics, Cape Town, South Africa: Partnerships for effective e-Health solutions

Journal of Pathology Informatics, 2011
The 13 th World Congress on Medical and Health Informatics (Medinfo) was held in 2010 between 12 and 15 September in Cape Town, South Africa. This triennial international gathering is the official conference of the International Medical Informatics ...
Andrew Georgiou
doaj   +1 more source

Clinical Informatics: Recursive Concurrence Intravenous Medication Administration Systems Protocols for Addressing the Potential Problem of Recessive Lethal Autonomy in Smart Infusion Systems [PDF]

arXiv, 2016
Smart Infusion Pumps are vital tools for use in administering a broad range of parenteral/intravenous medications. Safe and effective use of smart infusion pumps depends upon their integration with Pump Servers, Computerized Physician Order Entry Systems, Pharmacy Information Systems, DERS/MERS Dose/Medication Error Reduction Systems( and the digital ...
arxiv  

Single‐Cell Atlas Reveals Tumorigenic Profiles and Immune Dynamics of Adrenal Incidentalomas

Advanced Science, EarlyView.
Single‐cell RNA sequencing reveals cellular heterogeneity in adrenal incidentalomas, identifying distinct tumor cell populations. Clusterin is recognized as a biomarker for adrenocortical tumors, correlating with established markers. MYCN‐positive clusters in pheochromocytomas indicated poorer survival.
Meng Wang, Guangmin Zheng, Xiaoyong Hu, Feng Tian, Tuo Li, Zheng Zhang, Kan Gong, Shiwei Chen, Lin Yuan, Yu Qi, Lin Li, Daofu Cheng, Liu Liu, Fuqiang Liu, Yujing Sun, Xiangdong Fang, Ruxing Zhao, Bing Liu, Chao Zhang   +18 more
wiley   +1 more source