Results 191 to 200 of about 340,359 (301)

autoscoRA: Deep Learning to Automate Sharp/van der Heijde Scoring of Radiographic Damage in Rheumatoid Arthritis

open access: yesArthritis &Rheumatology, EarlyView.
Objective Regular imaging by conventional radiography to assess for joint damage is a cornerstone in the management of rheumatoid arthritis. Scoring systems to quantify such damage, such as the widely used Sharp/van der Heijde (SvdH) score, are limited by the requirement of time and experienced staff as well as intra‐ and interrater variability.
Thomas Deimel   +6 more
wiley   +1 more source

T Cell Plasticity in Systemic Lupus Erythematosus Revealed by Large‐Scale T Cell Receptor Repertoire and Transcriptome Studies

open access: yesArthritis &Rheumatology, EarlyView.
Objective We aimed to characterize CD4+ T cell plasticity in human systemic lupus erythematosus (SLE) by leveraging T cell receptor (TCR) repertoire features as markers of prior lineage states, integrating TCR and transcriptomic profiling to delineate plasticity patterns and evaluate their association with clinical disease activity. Methods We used TCR
Yasuo Nagafuchi   +11 more
wiley   +1 more source

The IM&T training needs of doctors in an acute UK NHS trust

open access: yes, 2003
Advanced information systems are seen as a key factor in plans to modernise the delivery of healthcare. In the UK, the General Medical Council and the Information Authority have stressed the need for doctors to possess not just IT skills, but more ...
Devvit, N, Murphy, J
core  

The role of IgM anti‐acetylated protein antibodies and B cells in the origin of anti‐modified protein autoimmunity in rheumatoid arthritis

open access: yesArthritis &Rheumatology, Accepted Article.
Objective Rheumatoid arthritis (RA) is characterized by anti‐modified protein antibodies (AMPAs), including anti‐citrullinated (ACPA), anti‐carbamylated (anti‐CarP), and anti‐acetylated (AAPA) protein antibodies. In contrast to other AMPAs, AAPA IgM is found in healthy individuals, raising questions about its role in early immune responses.
Aegli Athanasiadou   +10 more
wiley   +1 more source

Sleep‐trackers in the wild: A faceted taxonomy for information and interaction design

open access: yesJournal of the Association for Information Science and Technology, EarlyView.
Abstract Consumer‐grade sleep‐tracking technologies (CSTs) have brought sleep into everyday data practices, reframing it from a clinical concern into a site of personal optimization and reflection. Yet existing taxonomies of sleep‐tracking often medicalize users and overlook the complexity of sleep‐tracking technologies. This paper presents SleepTax, a
Sanonda Datta Gupta   +2 more
wiley   +1 more source

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