Results 261 to 270 of about 4,691,719 (361)

Paediatric developmental safety and the ICH E11A extrapolation of safety

open access: yes
British Journal of Clinical Pharmacology, EarlyView.
Gilbert J. Burckart   +6 more
wiley   +1 more source

Preserved Limbic White Matter Predicts Favorable 2‐Year Outcomes in Neonatal Hypoxic‐Ischemic Encephalopathy

open access: yesAnnals of the Child Neurology Society, EarlyView.
ABSTRACT Objective Accurate prediction of both favorable and unfavorable long‐term neurodevelopmental outcomes of neonatal hypoxic‐ischemic encephalopathy (HIE) is essential for clinical care, yet the brain structures underlying a favorable prognosis remain unclear.
Xingyu Chen   +10 more
wiley   +1 more source

Emerging medical informatics with case-based reasoning for aiding clinical decision in multi-agent system

open access: yesJournal of Biomedical Informatics, 2015
Ying Shen   +3 more
semanticscholar   +1 more source

Spotlight commentary: Addressing the persistent problem of benzodiazepine overuse, time for clinical, educational and AI‐driven reform

open access: yes
British Journal of Clinical Pharmacology, EarlyView.
Jakša Vukojević   +3 more
wiley   +1 more source

Results of the ACCOuNT Trial: A Multi‐Institutional Prospective Pharmacogenomics Implementation Trial for African American Inpatients

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Pharmacogenomics implementation efforts have increased over the last decade, but no published prospective pharmacogenomics trials have formally evaluated utility in underrepresented populations. We present final results from the ACCOuNT trial, a multi‐institutional prospective study [NCT03225820] in which African American inpatients were genotyped and ...
Zhong Huang   +17 more
wiley   +1 more source

Nonsteroidal Anti‐Inflammatory Drugs and Risk of Gastrointestinal Bleeding: A Systematic Review and Meta‐Analysis

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Nonsteroidal anti‐inflammatory drugs (NSAIDs) are widely used for pain and inflammation but are associated with gastrointestinal (GI) bleeding. While this risk is well established, most studies evaluate NSAIDs as a homogenous class, limiting clinical decision‐making based on individual agent safety.
Abdelrahman G. Tawfik   +7 more
wiley   +1 more source

Enhancing Severe Neutropenia Prediction: PKPD‐Informed Labeling for Machine Learning Models Trained on Real‐World Data

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Accurately labeling outcomes in real‐world data for machine learning is challenging due to data sparsity and imbalances. This study developed and evaluated a pharmacokinetic–pharmacodynamic (PKPD)‐informed labeling strategy to enhance the risk prediction of docetaxel‐induced neutropenia.
Conor J O’Hanlon   +9 more
wiley   +1 more source

An overview of data mining in medical informatics: Bangladesh perspective

open access: diamond, 2020
Mst. Farzana Akter   +3 more
openalex   +2 more sources

Home - About - Disclaimer - Privacy