Results 51 to 60 of about 4,299,186 (232)

IUPUI Center for Health Geographics [PDF]

, 2010
poster abstractThe IUPUI Center for Health Geographics develops and supports research innovation through integration of geographic information science, medical informatics, community informatics, and public health. Our areas of research emphasis include
Bodenhamer, David J., Comer, Karen Frederickson, Wilson, Jeffrey S.   +2 more
core  

Stereotyped Subclones Revealed by High‐Density Single‐Cell Lineage Tracing Support Robust Development

Advanced Science, EarlyView.
Based on a well‐established in vitro directed differentiation model and an integrated analysis of high‐density cell lineage trees (CLTs) and single‐cell transcriptomes, it is demonstrated that many subclones are formed by sub‐CLTs resembling each other in terms of both cell type compositions and topological structures.
Xiaoyu Zhang, Zizhang Li, Jingyu Chen, Wenjing Yang, Xingxing He, Peng Wu, Feng Chen, Ziwei Zhou, Chenze Ren, Yuyan Shan, Xiewen Wen, Vassily A. Lyubetsky, Leonid Yu. Rusin, Xiaoshu Chen, Jian‐Rong Yang   +14 more
wiley   +1 more source

Why Medical Informatics (still) Needs Cognitive and Social Sciences. [PDF]

, 2013
International audienceOBJECTIVES: To summarize current excellent medical informatics research in the field of human factors and organizational issues. METHODS: Using PubMed, a total of 3,024 papers were selected from 17 journals.
Aimé, Xavier, Declerck, Gunnar
core   +3 more sources

History of Medical Informatics - an Overview

Acta Informatica Medica, 2015
Health professionals are able to make right decision in right time only if they posses prompt, accurate and up to date information about health status of patients and general population.
Z. Sabanovic
semanticscholar   +1 more source

GDC: Integration of Multi‐Omic and Phenotypic Resources to Unravel the Genetic Pathogenesis of Hearing Loss

Advanced Science, EarlyView.
Overview of the Genetic Deafness Commons (GDC), integrating data from the Chinese Deafness Genetics Consortium (CDGC) and 51 public databases. The GDC provides tools for variant search, functional predictions, and gene‐disease visualization, offering insights into 201 hearing loss genes and facilitating novel gene discovery and clinical applications ...
Hui Cheng, Xuegang Wang, Mingjun Zhong, Jia Geng, Wenjian Li, Kanglu Pei, Jing Wang, Lanchen Wang, Yu Lu, Jing Cheng, Fengxiao Bu, Huijun Yuan   +11 more
wiley   +1 more source

The IM&T training needs of doctors in an acute UK NHS trust [PDF]

, 2003
Advanced information systems are seen as a key factor in plans to modernise the delivery of healthcare. In the UK, the General Medical Council and the Information Authority have stressed the need for doctors to possess not just IT skills, but more ...
Devvit, N, Murphy, J
core  

LRRC8A Regulates Outer Hair Cell Volume and Electromotility and is Required for Hearing

Advanced Science, EarlyView.
This study identifies LRRC8A‐dependent volume‐regulated anion channels (VRACs) as essential for cochlear outer hair cells' electromotility and auditory signal amplification. LRRC8A deficiency disrupts cell volume control, impairs auditory sensitivity, and causes deafness, while targeted LRRC8A re‐expression restores auditory function.
Shengnan Wang, Yuehui Xi, Qiaojun Fang, Sai Shi, Fei Wang, Fuyu Xian, Zhongyang Zhang, Yuxin Yang, Xishuo Jin, Xiaomin Wang, Chen Cao, Hailin Zhang, Nikita Gamper, Zhigang Xu, Haitao Shen, Ping Lv   +15 more
wiley   +1 more source

Heterointerface‐Modulated Synthetic Synapses Exhibiting Complex Multiscale Plasticity

Advanced Science, EarlyView.
An asymmetric dual‐gate heterointerface‐regulated artificial synapse (HRAS) is developed, employing distinct ion concentrations and dielectric coupling to form precise dual‐interface channels. Through lateral modulation, HRAS realizes, for the first time, the intricate interplay of lateral inhibition/enhancement and multi‐level short‐ and long‐term ...
Xingji Liu, Yao Ni, Zujun Wang, Sunfu Wei, Xiao′en Chen, Jingjie Lin, Lu Liu, Boyang Yu, Yue Yu, Dengyun Lei, Yayi Chen, Jianfeng Zhang, Jing Qi, Wei Zhong, Yuan Liu   +14 more
wiley   +1 more source

Gastrula‐Premarked Posterior Enhancer Primes Posterior Tissue Development Through Cross‐Talk with TGF‐β Signaling Pathway

Advanced Science, EarlyView.
A gastrula‐premarked enhancer within the first intron of Cdx2 governs posterior embryonic development via both regulating Cdx2 expression in cis and coordinating TGF‐β signaling in trans to ensure proper posterior body development. Functional rescue in gastruloids reveals a Cdx2‐independent pathway, highlighting p‐Enh‐eRNA as key epigenetic ...
Yingying Chen, Fengxiang Tan, Qing Fang, Lin Zhang, Jiaoyang Liao, Penglei Shen, Yun Qian, Mingzhu Wen, Rui Song, Yonggao Fu, He Jax Xu, Ran Wang, Cheng Li, Zhen Shao, Jinsong Li, Naihe Jing, Xianfa Yang   +16 more
wiley   +1 more source

Health informatics competencies in postgraduate medical education and training in the UK: a mixed methods study

BMJ Open, 2019
Objective To assess health informatics (HI) training in UK postgraduate medical education, across all specialties, against international standards in the context of UK digital health initiatives (eg, Health Data Research UK, National Health Service ...
Lydia Jidkov, M. Alexander, P. Bark, John G. Williams, J. Kay, P. Taylor, H. Hemingway, A. Banerjee   +7 more
semanticscholar   +1 more source