Results 81 to 90 of about 552,595 (324)

Density of States and Binding Energy Informatics for Exploring Early Disease Detection in MOF‐Metal Oxide Chemiresistive Sensors

Advanced Theory and Simulations, EarlyView.
Binding energy and electronic structure calculations are used to assess the ability of metal–organic framework (MOF)‐TiO2 composite materials to detect volatile organic compounds found in human breath. Electronic structure changes are measured by comparing density of states profiles using Wasserstein distances.
Maryam Nurhuda, Ken‐ichi Otake, Susumu Kitagawa, Daniel M. Packwood   +3 more
wiley   +1 more source

Personal Health Informatics: The Evolving Paradigm of Patient Self Care [PDF]

, 2014
The world of Biomedical informatics is dynamic, diverse and complex. Clinical informatics is a subset of biomedical informatics which specializes in patient care.
Rohm, B.W Trevor
core   +1 more source

GABP Promotes Mesangial Cell Proliferation and Renal Fibrosis Through GLI1 in Diabetic Nephropathy

Advanced Science, EarlyView.
GABP is found to promote mesangial cell proliferation and ECM deposition through GLI1, while inhibiting GABP or GLI1 prevents the progression of DN by reducing ECM and fibrosis. The research results indicate that a potential therapeutic approach based on inhibiting mesangial cell proliferation and ECM accumulation can effectively treat DN, while GABP ...
Lei Du, Sijie Liu, Yinfei Lu, Dongxue Ren, Xiujuan Yu, Yue Hu, Tingting Yang, Qun Yang, Jingxian Ming, Jiawei Zhang, Xiaoxing Yin, Qian Lu   +11 more
wiley   +1 more source

A powerful global test for spliceQTL effects

Biometrical Journal, Volume 65, Issue 1, January 2023., 2023
Abstract Statistical methods to test for effects of single nucleotide polymorphisms (SNPs) on exon inclusion exist but often rely on testing of associations between multiple exon–SNP pairs, with sometimes subsequent summarization of results at the gene level. Such approaches require heavy multiple testing corrections and detect mostly events with large
Renee X. de Menezes, Armin Rauschenberger, BIOS Consortium, Peter A. C. 't Hoen, Marianne A. Jonker   +4 more
wiley   +1 more source

Creating a pipeline of talent for informatics: STEM initiative for high school students in computer science, biology, and biomedical informatics

Journal of Pathology Informatics, 2014
This editorial provides insights into how informatics can attract highly trained students by involving them in science, technology, engineering, and math (STEM) training at the high school level and continuing to provide mentorship and research ...
Joyeeta Dutta-Moscato, Vanathi Gopalakrishnan, Michael T Lotze, Michael J Becich   +3 more
doaj   +1 more source

MORMED: towards a multilingual social networking platform facilitating medicine 2.0 [PDF]

, 2010
The broad adoption of Web 2.0 tools has signalled a new era of "Medicine 2.0" in the field of medical informatics. The support for collaboration within online communities and the sharing of information in social networks offers the opportunity for new ...
Bibikas, Dimitris, Boes, Ulrich, Kargioti, Eleni, Kourtesis, Dimitrios, Paraskakis, Iraklis   +4 more
core   +1 more source

MaTableGPT: GPT‐Based Table Data Extractor from Materials Science Literature

Advanced Science, EarlyView.
A significant challenge in materials informatics today is the creation of large‐scale experimental databases. This difficulty primarily stems from the complexities involved in consolidating locally distributed datasets from various laboratories into a single cohesive database.
Gyeong Hoon Yi, Jiwoo Choi, Hyeongyun Song, Olivia Miano, Jaewoong Choi, Kihoon Bang, Byungju Lee, Seok Su Sohn, David Buttler, Anna Hiszpanski, Sang Soo Han, Donghun Kim   +11 more
wiley   +1 more source

Current updates of CRISPR/Cas9‐mediated genome editing and targeting within tumor cells: an innovative strategy of cancer management

Cancer Communications, Volume 42, Issue 12, Page 1257-1287, December 2022., 2022
Abstract Clustered regularly interspaced short palindromic repeats‐associated protein (CRISPR/Cas9), an adaptive microbial immune system, has been exploited as a robust, accurate, efficient and programmable method for genome targeting and editing. This innovative and revolutionary technique can play a significant role in animal modeling, in vivo genome
Khaled S. Allemailem, Mohammed A Alsahli, Ahmad Almatroudi, Faris Alrumaihi, Fahd Khaleefah Alkhaleefah, Arshad Husain Rahmani, Amjad Ali Khan   +6 more
wiley   +1 more source

Classification Tree Diagrams in Health Informatics Applications [PDF]

arXiv, 2014
Health informatics deal with the methods used to optimize the acquisition, storage and retrieval of medical data, and classify information in healthcare applications. Healthcare analysts are particularly interested in various computer informatics areas such as; knowledge representation from data, anomaly detection, outbreak detection methods and ...
arxiv  

GDC: Integration of Multi‐Omic and Phenotypic Resources to Unravel the Genetic Pathogenesis of Hearing Loss

Advanced Science, EarlyView.
Overview of the Genetic Deafness Commons (GDC), integrating data from the Chinese Deafness Genetics Consortium (CDGC) and 51 public databases. The GDC provides tools for variant search, functional predictions, and gene‐disease visualization, offering insights into 201 hearing loss genes and facilitating novel gene discovery and clinical applications ...
Hui Cheng, Xuegang Wang, Mingjun Zhong, Jia Geng, Wenjian Li, Kanglu Pei, Jing Wang, Lanchen Wang, Yu Lu, Jing Cheng, Fengxiao Bu, Huijun Yuan   +11 more
wiley   +1 more source