Results 121 to 130 of about 6,930,270 (346)
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
Inside the Womb: Interpreting the Ferguson Case [PDF]
, 2002 The rise of globalization has made the sustainability aspect emerged as a sign that peoples’ actions must change. Tourism is now one of the fastest growing industries in the world that has an impact on people, nature and cultures.
Werauch, Samantha
core +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
A Case-Based Respiratory Microbiology Laboratory
MedEdPORTAL, 2013 Respiratory microbiology can be difficult for medical students to master as there are a plethora of pathogens that affect the respiratory tract.
Melphine Harriott
doaj +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Affordable Language Services: Implications for Health Care Organizations [PDF]
, 2007 Outlines the need to provide medical interpreters and healthcare material for patients with limited English proficiency. Summarizes RWJF's Hablamos Juntos initiative to develop affordable ways to remove language barriers and discusses lessons ...
core
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
(Over)Note-Taking in Consecutive Interpreting [PDF]
International Journal of English Language and Translation Studies, 2018 Interpreting trainees usually need some time and a lot of practice before they fully realize that note-taking in consecutive interpreting is only an aid to memory and a result of fully understanding what has been said, without paying too much attention ...
Maria T. Sanchez
doaj
LABRAD : Vol 33, Issue 3 - September 2008 [PDF]
, 2008 Vitamin D Deficiency: Are We Still Ignoring the Evidence? Collection and Transport of Urine for Culture Understanding and Interpreting Serum Protein Electrophoresis Cystic Fibrosis at a Glance What you need to know about Dengue Infection CT Colonoscopy ...
Aga Khan University Hospital, Karachi
core +1 more source
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source