Results 11 to 20 of about 119 (118)

Breakthrough Solution for Antimicrobial Resistance Detection: Surface‐Enhanced Raman Spectroscopy‐based on Artificial Intelligence

Advanced Materials Interfaces, EarlyView., 2023
This review discusses the use of Surface‐Enhanced Raman Spectroscopy (SERS) combined with Artificial Intelligence (AI) for detecting antimicrobial resistance (AMR). Various SERS studies used with AI techniques, including machine learning and deep learning, are analyzed for their advantages and limitations.
Zakarya Al‐Shaebi, Munevver Akdeniz, Awel Olsido Ahmed, Mine Altunbek, Omer Aydin   +4 more
wiley   +1 more source

Development of 4T1 breast cancer mouse model system for preclinical carbonic anhydrase IX studies

FEBS Open Bio, EarlyView.
Carbonic anhydrase IX (CAIX) is a well‐recognised therapeutic target and prognostic biomarker in cancer. We developed and characterised a robust murine breast cancer model system that is suitable for CAIX studies in vitro and in vivo—it comprises both CAIX‐positive and CAIX‐negative controls and provides a solid platform for the comprehensive ...
Zane Kalniņa, Ilva Liekniņa, Svetlana Koteloviča, Ramona Petrovska, Gediminas Žvinys, Agne Petrosiute, Asta Zubrienė, Matīss Toms Laugalis, Vendija Skeltona, Juris Jansons, Madara Kreishmane, Edita Čapkauskaitė, Daumantas Matulis, Kaspars Tārs   +13 more
wiley   +1 more source

Knockout of the mitoribosome rescue factors Ict1 or Mtrfr is viable in zebrafish but not mice: compensatory mechanisms underlying each factor's loss

FEBS Open Bio, EarlyView.
Mitochondria contain two mitoribosome rescue factors, ICT1 and MTRFR (C12orf65). ICT1 also functions as a mitoribosomal protein in mice and humans, and its loss is lethal. Although Mtrfr knockout mice could not be generated, knockout zebrafish lines for ict1 and mtrfr were established.
Nobukazu Nameki, Chika Tomisawa, Soichiro Hoshino, Hidehiko Shimizu, Masashi Abe, Sho Arai, Kanako Kuwasako, Naoki Asakawa, Yusuke Inoue, Takuro Horii, Izuho Hatada, Masakatsu Watanabe   +11 more
wiley   +1 more source

Surface dose analysis and dosimetric comparison of Halcyon versus Truebeam in breast cancer radiotherapy: An OSL dosimetry study

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose Breast cancer is a neoplastic disease with high prevalence among women. Radiotherapy is one of the principal treatment modalities for this disease, but it poses significant challenges. This study aimed to compare and evaluate the technical and dosimetric performance of conventional C‐arm linac systems and a new design, Halcyon, in the ...
Mustafa Çağlar, Kudret Akçay, Esra Serin, Dursun Eşitmez, Mehmet Sıddık Cebe, Navid Kheradmand, Ömer Yazıcı, Dilek Ünal, Evrim Metcalfe   +8 more
wiley   +1 more source

AAPM Task Group No. 249.B—Essentials and guidelines for clinical medical physics residency training program

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract The establishment of guidelines and curriculum standards for medical physics residency training is a critical component of setting expectations and competencies for the profession. Since the last publication of these standards, residency training has become integrated into the eligibility criteria for most medical physics certification bodies.
Jonathon A. Nye, Joseph P. Dugas, William D. Erwin, David P. Gierga, Darryl G. Kaurin, Stephanie M. Leon, Ho‐Ling Anthony Liu, Zheng Feng Lu, Alphonso W. Magri, Lynn N. Rill, Leah K. Schubert, Beth A. Schueler, Irina Vergalasova, John Vetter, Brian D. Wichman, Amy Shu‐Jung Yu, Dandan Zheng   +16 more
wiley   +1 more source

Enhanced Mechanical Properties of Injectable Chitosan–Guar Gum Hydrogel Reinforced with Bacterial Cellulose Nanofibers for Tissue Engineering Applications

Advanced Engineering Materials, EarlyView.
This study presents the development and characterization of injectable nanocomposite hydrogels based on N‐succinyl chitosan, oxidized guar gum, and bacterial cellulose nanofibers. Emphasizing enhanced mechanical properties and biocompatibility, the hydrogels exhibit fast gelation, improved structural integrity, and reduced swelling. Their potential for
Raimundo Nonato Fernandes Moreira Filho, Pascale Chevallier, Silvia Rodriguez Fernandez, Maud Viallon, Matheus Xavier de Oliveira, Ana Lorena de Brito Soares, Diego Mantovani, Judith Pessoa de Andrade Feitosa, Rodrigo Silveira Vieira   +8 more
wiley   +1 more source

Asymmetric Nanofiber Membranes for Simultaneous Moisture Adsorption and Rapid Catalytic Hydrolysis of Nerve Agent Simulants in Atmospheric Environments

Advanced Functional Materials, EarlyView.
Asymmetric nanofiber membranes are constructed for simultaneous moisture adsorption and catalytic hydrolysis of dimethyl 4‐nitrophenyl phosphate (DMNP) in a wide range of relative humidity. The membrane exhibits high moisture adsorption capacity and fast hygroscopic rate.
Xuejiao Wang, Yu‐Xuan Zheng, Chen Ding, Ming Zhang, Zhong‐Zhen Yu, Shaobin Wang, Dongzhi Yang   +6 more
wiley   +1 more source

Delivery of Islatravir via High Drug‐Load, Long‐acting Microarray Patches for the Prevention or Treatment of Human Immunodeficiency Virus

Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
Islatravir‐loaded dissolving microarray patches (MAPs) provide a minimally invasive, long‐acting solution for HIV‐1 prevention and treatment. In rats, sustained islatravir delivery lasts up to three months, while in minipigs, efficacious plasma levels are detected for six days.
Qonita Kurnia Anjani, Ashley R. Johnson, Akmal H. Sabri, Ryan Lutz, Steven Tignor, Jeanine Ballard, Nathan Rudd, Li Zhao, Lalitkumar K. Vora, Stephanie E. Barrett, Angela Wagner, Ryan F. Donnelly   +11 more
wiley   +1 more source

Immunosuppressive Formulations for Immunological Defense against Traumatic Brain Injury

Advanced Healthcare Materials, EarlyView.
A novel subcutaneous formulation combining alpha‐ketoglutarate, glycolysis inhibitor PFK15, and a myelin peptide reduces inflammation in a mouse TBI model. This formulation promotes regulatory immune cells, enhances autophagy, and improves motor function, suggesting its potential as a prophylactic immunosuppressive therapy to mitigate TBI‐induced ...
Kelly Lintecum, Abhirami Thumsi, Kara Dunn, Lindsey Druschel, Sierra Chimene, David Flores Prieto, Amberlyn Simmons, Shivani Mantri, Arezoo Esrafili, Srivatsan J. Swaminathan, Mytreyi Trivedi, Shreya Anandan, Crystal Willingham, Alondra Davila, Sahil Inamdar, Joslyn L. Mangal, Abhirami P. Suresh, Niveda M. Kasthuri, Madan Mohan Chandra Sekhar Jaggarapu, Nicole Appel, Taravat Khodaei, Nathan D. Ng, Alison Sundem, Sanmoy Pathak, George Bjorklund, Jason Newbern, Jeffrey Capadona, Sarah E. Stabenfeldt, Abhinav P. Acharya   +28 more
wiley   +1 more source

Advancing Metal–Organic Framework‐Based Composites for Effective Chemical Warfare Agent Detoxification under Real‐World Conditions

Advanced Materials, EarlyView.
This review describes recent developments in the design and synthesis of metal–organic frameworks (MOF)/textile composites for the detoxification of chemical warfare agent and simulants with extensive discussion on the advantages and disadvantages of different methods.
Zhihua Cheng, Kira M. Fahy, Gregory W. Peterson, Kent O. Kirlikovali, Omar K. Farha   +4 more
wiley   +1 more source