Results 231 to 240 of about 502,071 (301)

A Novel Air‐Liquid Interface Exposure System for Continuous Gas Exposure of Airway Epithelial Cells: Exposure of NO2 With Viral Co‐Challenge

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Most in vitro toxicological research investigating the effects of inhaled compounds employ short‐term exposures of a couple of hours, or repeated, intermittent exposures for a limited number of days with exposure free periods, whereas in reality, we are continuously exposed, albeit to variable concentrations.
Marcia M. Oldenburger   +4 more
wiley   +1 more source

Building a Beta-Lactam Model-Informed Precision Dosing Service in a Quaternary Care Children's Hospital. [PDF]

open access: yesClin Transl Sci
Tang Girdwood S   +12 more
europepmc   +1 more source

Subchronic Exposure to Arsenic and Nickel Triggers Nitrosative Stress and Histological Alterations in the Rat Liver

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Environmental exposure to heavy metals poses a threat to human health. Several studies documented harmful effects on the liver after arsenic and nickel exposure at concentrations beyond permissible limits. Nevertheless, the impact of a simultaneous exposure to both elements on hepatic biochemistry and histology remains unelucidated. Therefore,
Thainá Iasbik‐Lima   +4 more
wiley   +1 more source

Evaluation of DNA/Chromosome Integrity and Cell Death in Human Metabolically Noncompetent and Competent Cells Exposed to N′‐(3,5‐Difluorobenzylidene)Pyridine‐4‐Carbohydrazide

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT The N‐acylhydrazone scaffold is recognized as a privileged structure for the design of bioactive substances with increasing applications in medicinal chemistry research. Ensuring the safety of newly developed molecules is a critical step for both human health and environmental protection. Accordingly, this study aimed to evaluate the cytotoxic
Larissa Ribeiro Canuto Santos   +4 more
wiley   +1 more source

Integrated ESR and PLT‐H Measurement Using the BC‐6800 Plus Hematology Analyzer: A Comprehensive Analytical Evaluation

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
This study evaluated the analytical performance of the Mindray BC‐6800 Plus hematology analyzer, focusing on integrated erythrocyte sedimentation rate (ESR) and hybrid platelet counting (PLT‐H). Results demonstrated excellent background suppression, precision, linearity, and robustness across different modes and analyzers, confirming its reliability ...
Meilin Chen   +4 more
wiley   +1 more source

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