Results 61 to 70 of about 119 (118)

Ethnomedicinal Uses, Phytochemistry, Pharmacological Activities, and Toxicology of the Subfamily Gomphrenoideae (Amaranthaceae): A Comprehensive Review

Chemistry &Biodiversity, EarlyView.
ABSTRACT The subfamily Gomphrenoideae is composed of about 480 accepted species, many of which have been historically used as medicinal plants, reason why they have been studied in terms of chemical profile, biological activity, and safety. This review consolidates the advances in research on this subfamily over the past 47 years, emphasizing its ...
Dayanna Isabel Araque Gelves, Giulia Cristina de Andreoli Souza, Alvaro Jose Hernandez Tasco, Marcos José Salvador   +3 more
wiley   +1 more source

Fractional Flow Reserve Directed Percutaneous Coronary Intervention Optimization Using High‐Definition Intravascular Ultrasound in Non‐ST‐Segment Elevation Acute Coronary Syndrome Versus Chronic Coronary Syndrome

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Intravascular ultrasound (IVUS)‐guided optimization of suboptimal fractional flow reserve (FFR) following percutaneous coronary intervention (PCI) results in a significant increase in both post‐PCI FFR and minimal lumen and stent areas (MLA and MSA, respectively).
Frederik T. W. Groenland, Tara Neleman, Annemieke C. Ziedses des Plantes, Alessandra Scoccia, Isabella Kardys, Wijnand K. den Dekker, Jeroen M. Wilschut, Roberto Diletti, Nicolas M. Van Mieghem, Joost Daemen   +9 more
wiley   +1 more source

Performance of Computer‐Aided Detection Software in Tuberculosis Case Finding in Township Health Centers in China

Chronic Diseases and Translational Medicine, EarlyView.
Flow chart of the study implementation. ABSTRACT Background Computer‐aided detection (CAD) software has been introduced to automatically interpret digital chest X‐rays. This study aimed to evaluate the performance of CAD software (JF CXR‐1 v3.0, which was developed by a domestic Hi‐tech enterprise) in tuberculosis (TB) case finding in China. Methods In
Xuefang Cao, Boxuan Feng, Bin Zhang, Dakuan Wang, Jiang Du, Yijun He, Tonglei Guo, Shouguo Pan, Zisen Liu, Jiaoxia Yan, Qi Jin, Lei Gao, Henan Xin   +12 more
wiley   +1 more source

Laser‐Induced Graphene for Early Disease Detection: A Review

ChemElectroChem, Volume 12, Issue 6, March 15, 2025.
Laser‐induced graphene (LIG) has emerged as a superior alternative to conventionally synthesized graphene due to its flexibility, cost‐effectiveness, scalability, high conductivity, and the ability to customize its properties for various applications. This review highlights LIG′s transformative potential in electrochemical biosensing, focusing on early
Sri Ramulu Torati, Gymama Slaughter
wiley   +1 more source

Antibacterial and antiviral activity of a highly efficient electrospun r‐PET nanofiber

The Canadian Journal of Chemical Engineering, EarlyView.
Abstract Since the COVID‐19 pandemic, the emergence of clean air has increased interest in developing antimicrobial air filters, targeting sterilization and public health concerns. Nanofibers are a promising approach due to their high efficiency in air filtration, while nanoparticles adhered to the fibre surfaces can improve safety due to the biocidal ...
Karine Machry, Danilo M. Melo, Daniela Patrícia Freire Bonfim, Paulo Augusto Marques Chagas, Felipe de Aquino Lima, Clovis Wesley Oliveira de Souza, Luiz Tadeu Moraes Figueredo, Mônica Lopes Aguiar, André Bernardo   +8 more
wiley   +1 more source

Chemometrics‐Assisted Electrochemical Device for Cannabidiol Detection in Real Cannabis sativa Samples

Chemistry–Methods, EarlyView.
GA: Four‐step process for cannabidiol (CBD) detection in Cannabis sativa extracts. (1) The plant extract is obtained. (2) An electrochemical sensor detects CBD using a screen‐printed electrode. (3) Electrochemical signatures of real samples are recorded, showing current vs. potential curves.
Wanda Cimmino, Ada Raucci, Antonella Miglione, Ciro Ascione, Ernesto Gargiulo, Nunzio Fiorentino, Serena Detti, Claudio D’Alfonso, Chiara Nieri, Sabino Napoletano, Antonietta Lombardozzi, Ibrahim A. Darwish, Giuseppina Chianese, Stefano Cinti   +13 more
wiley   +1 more source

Effect of Mild to Moderate Hepatic Impairment on Valemetostat Pharmacokinetics: An Open‐Label, Phase I Study

Clinical Pharmacology in Drug Development, EarlyView.
Abstract Valemetostat tosylate (valemetostat) is a dual inhibitor of enhancer of zeste homolog (EZH) 2 and EZH1, approved in Japan for the treatment of relapsed/refractory peripheral T‐cell lymphoma and adult T‐cell leukemia/lymphoma. This Phase I, open‐label study evaluated the pharmacokinetics and safety of a single 50‐mg oral dose of valemetostat in
Masaya Tachibana, Thuy Vu Craveiro, Thomas C. Marbury, Samuel Oberstein, George J. Atiee, Ben Tao, Takako Shimizu, Yvonne Lau, Malaz A. Abutarif   +8 more
wiley   +1 more source

Nicotinamide riboside and pterostilbene reduces markers of hepatic inflammation in NAFLD: A double‐blind, placebo‐controlled clinical trial

Hepatology, EarlyView., 2022
NRPT 1X reduces ALT and ceramide 14:0 in 65% of subjects as compared to only 28% in the placebo group. Abstract Background and Aims The prevalence of NAFLD is increasing globally and on a path to becoming the most frequent cause of chronic liver disease. Strategies for the prevention and treatment of NAFLD are urgently needed.
Ryan W. Dellinger, Holly E. Holmes, Tina Hu‐Seliger, Rodney W. Butt, Stephen A. Harrison, Dariush Mozaffarian, Oliver Chen, Leonard Guarente   +7 more
wiley   +1 more source

A Randomized Thorough QT Trial Using Concentration‐QT Analysis to Evaluate the Effects of Centanafadine on Cardiac Repolarization

Clinical Pharmacology in Drug Development, EarlyView.
Abstract Centanafadine is a norepinephrine/dopamine/serotonin reuptake inhibitor in development for treatment of attention‐deficit/hyperactivity disorder. This double‐blind, placebo‐ and moxifloxacin‐controlled, 3‐period crossover trial evaluated the effects of centanafadine (EB‐1020) and its metabolite (EB‐10601) on cardiac repolarization in 30 ...
Osman S. Turkoglu, Xiaofeng Wang, Jennifer Repella‐Gordon, Susan E. Shoaf   +3 more
wiley   +1 more source

ESR1 Variants and Subcontinental Genomic Ancestry: Insights from the 1000 Genomes Project and Native American Populations

Clinical Pharmacology &Therapeutics, EarlyView.
The ESR1 gene is relevant in breast cancer treatments in the pharmacogenetics context. However, Native, African, and mixed populations are known to be underrepresented in genomic studies. This is particularly important given that the difference in variants' frequencies among different populations can lead to population‐specific clinical implications ...
Mariana M. Scudeler, Caíque Manóchio, Bruno Miwa, Guilherme Belfort‐Almeida, Lucas Faria‐Costa, Cesar Sanchez, Carlos Padilla, Omar Caceres, Eduardo Tarazona‐Santos, Heinner Guio, Timothy D. O'Connor, Fernanda Rodrigues‐Soares   +11 more
wiley   +1 more source