Results 71 to 80 of about 502,071 (301)

A Metal‐Free Carbon Monoxide Prodrug Suppresses Metastasis of Pancreatic and Breast Cancer

Advanced Science, EarlyView.
A metal‐free carbon monoxide (CO) prodrug, CO‐116, delivers controlled systemic CO without inhalation. CO suppresses the HRG1–heme axis, reducing intracellular heme availability. Attenuation of this pathway inhibits metastatic progression in pancreatic and triple‐negative breast cancer models.
Tiantian Zhang, Xiang Chen, Xiaoxiao Yang, Muskan Gori, Rohit Kumar Varshnaya, Dongning Liu, Cheryl Zhang, Michelle Yi Qin Chen, Zhengming Chen, George Zhang, Erika Patel, Qiyue Mao, Tan A. Ince, Chalet Tan, Binghe Wang, Yi‐Chieh Nancy Du   +15 more
wiley   +1 more source

Awareness and Practice of Biomedical Waste Management Among Different Health Care Personnel at Tertiary Care Centre, Rajkot, India

Online Journal of Health & Allied Sciences, 2014
Background: Bio medical waste collection and proper disposal has become a significant concern for both the medical and general community. Objective: To know the awareness and practice of biomedical waste management (BMW) among health care personnel ...
Rajesh K Chudasama, Ankit Sheth, Matib Rangoonwala, Nirav Joshi, Dipesh Zalavadiya, Chirag Bhola   +5 more
doaj  

Analysis of compliance issues and influencing factors in the management of BSL-2 laboratories for pathogenic microorganisms in Lishui, China

Frontiers in Bioengineering and Biotechnology
BackgroundThe management of biosafety laboratories for pathogenic microorganisms is directly related to public health and the effectiveness of biological experiments.
Ying Cong, Jinkai Li, Dingshuo Lou, Jianliang Zhu, Deyong Zhang, Dongqing Cheng, Xiuying Chen   +6 more
doaj   +1 more source

Introducing an Endocrine Laboratory

Journal of Pathology of Nepal, 2018
The growing sub-specialty in Medical practice is beneficial for the patient as well as for the healthcare providers. Laboratory Medicine is also an emerging field to address the complexity of health arena.
Vivek Pant
doaj   +1 more source

A NeuroD1 AAV‐Based Gene Therapy for Functional Brain Repair in Alzheimer's Disease‐Like Non‐Human Primate Model

Advanced Science, EarlyView.
This study tests NeuroD1 AAV‐based gene therapy in a non‐human primate Alzheimer's disease model. The therapy prevents neuronal damage, inhibits hippocampal atrophy, and reduces neuroinflammation. It also repairs vascular and blood‐brain barrier damage, restores cerebrospinal fluid biomarkers, enhances hippocampal glucose metabolism, and improves ...
Zhouquan Jiang, Yongpeng Qin, Bin Luo, Fan Bai, Jiangyue Liu, Long Ma, Shu He, Rongjie Chen, Yuchen Wang, Shanggong Liu, Ying Sun, Yi Chen, Shuo Zhang, Jiaqi Liang, Feng Liao, Huiyi Wei, Junjie Wei, Lu Wang, Hao Xu, Zheng Wu, Gong Chen, Wenliang Lei   +21 more
wiley   +1 more source

Implementing Operations Support Systems in E-Health Based Systems [PDF]

, 2007
Information and communication technologies have been introduced in different dimensions of the health care. e-Health is the use of advanced communications technologies such as the Internet, portable, wireless and other sophisticated devices to support ...
Ayo, C. K., Ehikioya, S.A., Omoregbe, N. A.   +2 more
core  

NUDT21 Drives T‐Cell Acute Lymphoblastic Leukemia Through Dual Regulation of Alternative Polyadenylation and Transcriptional Activation

Advanced Science, EarlyView.
In summary, our study defines a coordinated oncogenic model in which NUDT21 integrates alternative polyadenylation–dependent UBE2D3 stabilization and transcriptional activation to sustain MYC‐driven T‐ALL cell survival, thereby establishing NUDT21 as a central regulatory node and a promising therapeutic target.
Conglian Qiu, Jianwei Wang, Zhiheng Li, Qi Ji, Hui Zhang, Qinyi Zhang, Senlin Zhang, Juanjuan Yu, Yanfang Tao, Yijun Wu, Chunxia Shi, Zong Zai, Zimu Zhang, Yizhen Li, Zhenjiang Bai, Shaoyan Hu, Jian Pan, Yang Yang, Shuiyan Wu   +18 more
wiley   +1 more source

Human resources for control of tuberculosis and HIV-associated tuberculosis. [PDF]

, 2005
The global targets for tuberculosis (TB) control were postponed from 2000 to 2005, but on current evidence a further postponement may be necessary.
Bergström, K, Blanc, L, Elzinga, G, Harries, A D, Salaniponi, F, Zachariah, R   +5 more
core   +1 more source

Organisation of Health Care During an Outbreak of Marburg Haemorrhagic Fever in the Democratic Republic of Congo, 1999. [PDF]

, 2004
Organising health care was one of the tasks of the International Scientific and Technical Committee during the 1998-1999 outbreak in Durba/Watsa, in the north-eastern province (Province Orientale), Democratic Republic of Congo.
Borchert, M, Colebunders, R, Kinuani, L, Libande, M, Mustin, J P, Muyembe-Tamfum, J J, Olinda, L A, Pirard, P, Sleurs, H, Tshioko, F, Tshomba, A   +10 more
core   +2 more sources

Integrating Spatial Proteogenomics in Cancer Research

Advanced Science, EarlyView.
Xx xx. ABSTRACT Background: Spatial proteogenomics marks a paradigm shift in oncology by integrating molecular analysis with spatial information from both spatial proteomics and other data modalities (e.g., spatial transcriptomics), thereby unveiling tumor heterogeneity and dynamic changes in the microenvironment.
Yida Wang, Yang Wu, Feng Zhang, Parthiban Periasamy, Haiyue You, Denise Goh, Rachel Elizabeth Ann Fincham, Xin Ning, Danping Wu, Lu Liu, Ying Jiang, Zhiwen Qian, Joe Yeong, Yan Zhang   +13 more
wiley   +1 more source