Results 71 to 80 of about 119 (118)

Tackling Environmental Impact: A New Support Tool for Sustainable Healthcare Waste Management

Corporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT This study proposes a novel framework integrating Environmental Risk Assessment (ERA) and Material Flow Analysis (MFA) within the Deming Cycle framework to address this gap. While valuable tools, ERA and MFA offer limited perspectives on environmental impact when used alone.
Carlotta D'Alessandro, Katarzyna Szopik‐Depczyńska, Raffaella Taddeo, Katarzyna Cheba, Giuseppe Ioppolo   +4 more
wiley   +1 more source

Rethinking Chlorine: Essential Chemical or Replaceable Risk?

ChemSusChem, EarlyView.
Chlorine is essential for the production of plastics and pharmaceuticals but poses significant safety and environmental risks. Herein, processes are presented that substitute chlorine or reduce its demand. Where indispensable, trichloride‐ and bichloride‐based ionic liquids could enhance safety and streamline the integration of renewable energy ...
Johannes Schwan, Merlin Kleoff, Gesa H. Dreyhsig, Patrick Voßnacker, Traute Fiedler, Marian Rosental, Sebastian Riedel   +6 more
wiley   +1 more source

OMIP‐115: High‐Dimensional Phenotypic Characterization of Human Natural Killer Cells for Therapeutic Use

Cytometry Part A, EarlyView.
ABSTRACT This 29‐color flow cytometry panel was developed and optimized for in‐depth characterization of human peripheral blood NK cells for preclinical development and monitoring of NK cell therapies. The panel includes markers associated with NK cell differentiation, cytotoxicity, tissue residency, as well as NK cell dysfunction.
Emil Birch Christensen, Moritz Schaefer, Mike Bogetofte Barnkob, Christian Nielsen, Torben Barington   +4 more
wiley   +1 more source

Automated analysis of flow cytometry data with minimal training files: Research evaluation of an elastic image registration algorithm for TBNK, stem cell enumeration, and lymphoid screening tube assays

Cytometry Part B: Clinical Cytometry, EarlyView.
Abstract Automated analysis of flow cytometry data can improve objectivity and reduce analysis time but has generally required work by software and algorithm experts. Here, we investigated the performance of BD ElastiGate™ Software (hereafter ElastiGate), which allows users to automate gating by selecting gated training files, then uses elastic image ...
Allison Irvine, Suhail Tahir, Vishnu Tripathi, Farzad Oreizy, Moen Sen, Anthony Giuliano, Anna Lin, Angela Chen, Chih‐Hung Lai, Imelda Omana‐Zapata, Yang Zeng, Paresh Jain, Scott J. Bornheimer   +12 more
wiley   +1 more source

Clinical validation of a real‐time machine learning‐based system for the detection of acute myeloid leukemia by flow cytometry

Cytometry Part B: Clinical Cytometry, EarlyView.
Abstract Machine‐learning (ML) models in flow cytometry have the potential to reduce error rates, increase reproducibility, and boost the efficiency of clinical labs. While numerous ML models for flow cytometry data have been proposed, few studies have described the clinical deployment of such models.
Lauren M. Zuromski, Jacob Durtschi, Aimal Aziz, Jeffrey Chumley, Mark Dewey, Paul English, Muir Morrison, Keith Simmon, Blaine Whipple, Brendan O'Fallon, David P. Ng   +10 more
wiley   +1 more source

Interest of hair tests to discriminate a tail end of a doping regimen from a possible contamination in case of challenging an anti‐doping rule violation. V. Case reports involving trimetazidine, a drug where the concentration after a single 20 mg dose has been established

Drug Testing and Analysis, EarlyView.
From ingestion to hair incorporation Abstract The identification of trimetazidine, a medicine used for treating stable angina pectoris and for preventing angina attacks, has been recently observed in doping cases involving high profile athletes from various countries over the world.
Pascal Kintz, Alice Ameline, Laurie Gheddar   +2 more
wiley   +1 more source

Pharmacokinetics of Two Formulations of Altrenogest Administered to Mares

Drug Testing and Analysis, EarlyView.
Pharmacokinetics of altrenogest in mares to determine expected concentrations of plasma altrenogest associated with oral and intramuscular administration. Quantification of altrenogest in mares is of increasing importance with prohibited formulations and restrictions on administration.
Jaymie Loy, Adam Cawley, Kireesan Sornalingam, Colin J. Scrivener, John Keledjian, Glenys K. Noble   +5 more
wiley   +1 more source

Cost Minimized Immunoaffinity Purification of EPO and Its Analogs in Doping Control—A Step‐by‐Step Protocol for Human Urine and Blood

Drug Testing and Analysis, EarlyView.
A cost minimized immunoaffinity protocol was developed, which allows the direct purification of ERAs from human urine. After slight modification, the protocol is also applicable to serum and plasma and is fully compliant with WADA TD2024EPO. Compared to commercial EPO‐purification kits, the material costs are significantly lower.
Christian Reichel, Günter Gmeiner, Mario Thevis   +2 more
wiley   +1 more source

Rapid and Simple Dispersive Liquid–Liquid Microextraction (DLLME) Sample Preparation for Propofol Analysis in Hair, Blood, and Urine by Gas Chromatography–Mass Spectrometry

Drug Testing and Analysis, EarlyView.
Development and validation of an extraction method based on dispersive liquid–liquid microextraction for the analysis by GC–MS of propofol in three different biological samples (blood, urine, and hair). The proposed method is very simple and rapid.
Sara Odoardi, Serena Mestria, Valeria Valentini, Giulia Biosa, Sabina Strano Rossi   +4 more
wiley   +1 more source

Anti‐Doping Testing at FIFA World Cup 2022

Drug Testing and Analysis, EarlyView.
The FIFA 2022 World Cup was fully accomplished by the Anti‐Doping Lab Qatar. The article describes the doping analysis work, achievements, and lab structure in details. ABSTRACT The 22nd FIFA World Cup, the world championship for national football teams, was held in Qatar from November 20th to December 18th, 2022.
Alanod D. AlQahtani, Wadha Abushareeda, Ariadni Vonaparti, Suhail Kraiem, Wesal ElSaftawy, Khadija Saad, Aisha Al‐Wahaibi, Nayla Hilal, Najib Dbes, Vandana Nimker, Alexis Weber, Alka Beotra, Mohammed Al Maadheed   +12 more
wiley   +1 more source