The study evaluated the function and therapeutic implications of PRAME in basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). The findings demonstrate that PRAME impairs keratinocyte differentiation pathways. Furthermore, PRAME impairs anticancer response to retinoid compounds in BCC and SCC cells.
Brandon Ramchatesingh+6 more
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Thomas Schlich, The Origins of Organ Transplantation: Surgery and Laboratory Science, 1880–1930, Rochester Studies in Medical History, Volume 18 (Rochester: University of Rochester Press, 2010), pp. x + 355, £45.00, hardback, ISBN: 978-1- 58046-353-9. [PDF]
Miran Epstein
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CircCCNB1 expression is down‐regulated in nasopharyngeal carcinoma (NPC); thus, less NF90 protein is bound to circCCNB1 and more binds to pri‐miRNAs, blocking their (pri‐miRNAs) binding to DGCR8 and inhibiting the processing and generation of miR‐15b‐5p/miR‐7‐1‐3p. Furthermore, decreased miR‐15b‐5p/miR‐7‐1‐3p promotes the expression of the target genes
Chunmei Fan+6 more
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1995 Survey of Medical Laboratory Science Programs [PDF]
Barbara M. Castleberry+2 more
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Annual Reports from Division of Biochemistry, Central Laboratory for Medical Sciences
研 究報告会, 数 個
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Schlich, Thomas: The Origins o f Organ Transplantation. Surgery and Laboratory Science. 1880–1930. Rochester, University of Rochester Press, 2010. 3 55 p. I ll. (Rochester Studies in Medical History). $ 80. ISBN 978-1-58046-353-9 [PDF]
R. Hammer
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Classification of acute myeloid leukemia based on multi‐omics and prognosis prediction value
The Unsupervised AML Multi‐Omics Classification System (UAMOCS) integrates genomic, methylation, and transcriptomic data to categorize AML patients into three subtypes (UAMOCS1‐3). This classification reveals clinical relevance, highlighting immune and chromosomal characteristics, prognosis, and therapeutic vulnerabilities.
Yang Song+13 more
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Annual Reports from Division of Pathology, Central Laboratory for Medical Sciences
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Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi+26 more
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