Results 111 to 120 of about 978,736 (284)
Metabolic and biochemical profiling reveals phenotypic heterogeneity in Zucker diabetic fatty rats
Animal Models and Experimental Medicine, EarlyView.Genetically uniform Zucker Diabetic Fatty (ZDF) rats spontaneously develop four distinct metabolic phenotypes despite identical housing and diet conditions. Each phenotype exhibits unique biomarker signatures encompassing glucose homeostasis, insulin secretion, polyol pathway activation, oxidative stress, inflammatory cytokines, and neurotrophic ...
Marek Lepáček +3 more
wiley +1 more source
Advanced NanoBiomed Research, EarlyView.Lysyl oxidase crosslinking of type I collagen decreases neutrophil extravasation through an endothelium during the initial response to P. aeruginosa. This decrease in extravasation is likely due to the increase in VE‐cadherin expression between endothelial cells seeded on LOX‐crosslinked collagen hydrogels.
Christopher J. Calo +7 more
wiley +1 more source
Ethnicity and the surgical management of early invasive breast cancer in over 164 000 women
BJS (British Journal of Surgery), EarlyView., 2020 This large national study examined in detail the patterns in surgical management of early breast cancer in women of different ethnicities. Allowing for different patterns of age and stage at presentation, the surgical management of early breast cancer was similar in all women, regardless of ethnicity. All treated the same Background Limited information
T. Gathani +4 more
wiley +1 more source
Animal Research and One Health, EarlyView.Palatability enhancers modulate taste and smell, increasing feed acceptance, reducing weaning stress, and improving piglet performance. ABSTRACT The continuous growth of global agribusiness stimulates the search for alternatives that can enhance the performance and quality of life of production animals.
Luana Specht +3 more
wiley +1 more source
Animal Research and One Health, EarlyView.Intensive or organic farming systems may expose pigs to management or environmental challenges. Our preliminary results concluded that organic farming might enhance adaptive immune function, showing that improvements in welfare can translate into measurable immunological benefits, based on the correlation between welfare assessment and physiological ...
Dorotea Ippolito +15 more
wiley +1 more source
Analysis and improving countermeasures of medical disputes from the perspective of legal changes
Journal of OtologyUnder the background of medical disputes growing in number, scale and intensity, tracing back legal changes in medical field as a breakthrough point, this paper took a legal perspective to illustrate changes in medical dispute settlements from ...
Zhang Linlin, Zhang Shimeng
doaj +1 more source
The United States Leads the Globe in Venture Capital Funding for Orthopaedic Surgery
Arthroscopy, Sports Medicine, and Rehabilitation, EarlyView.Purpose To characterize venture capital (VC) investments in orthopaedic surgery over the past 25 years to evaluate trends in global innovation. Methods All VC investments related to orthopaedic surgery between January 2000 and December 2024 were retrospectively evaluated using the PitchBook database (PitchBook Platform, PitchBook Data.
Mathangi Sridharan +7 more
wiley +1 more source
Costs of treating type 2 diabetes mellitus and its complications
Biotechnology & Biotechnological EquipmentThe major driver of the costs of treating patients with diabetes mellitus type 2 (DM2) is its complications, which in developing countries are a consequence of poor glycemic control due to the low availability of novel, innovative antidiabetic drugs.
Nemanja Petrović +6 more
doaj +1 more source
Children in need of medical innovation [PDF]
Children are therapeutic orphans and an underprivileged group in innovations derived from drug therapy. As the innovation process of pharmaceuticals is a long, risky and very costly business, economists typically emphasise lack of profit incentives and ...
Entorf, Horst +2 more
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The Value of Clinical Practice Guidelines as Malpractice "Safe Harbors" [PDF]
, 2012 Examines the extent to which evidence-based recommendations for optimizing patient care could help reduce provider defensiveness and overutilization.
Randall R. Bovbjerg, Robert A. Berenson
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