Results 31 to 40 of about 964,648 (316)

‘The dangers attending these conditions are evident’: public health and the working environment of Lancashire textile communities, c.1870–1939 [PDF]

, 2013
This article examines the position of the working environment within public health priorities and as a contributor to the health of a community. Using two Lancashire textile towns (Burnley and Blackburn) as case studies and drawing on a variety of ...
Greenlees, Janet
core   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Medical Expertise at Yekaterinburg Hospital: Legislation and Practice in 1720s–1750s

Научный диалог
This article examines the process of conducting medical expertise at the Yekaterinburg Hospital during the years 1720 to 1750. It highlights that medical examination was mandated by legislation in cases of early resignation from factory service due to ...
A. Plate
doaj   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Correlation Between Malpractice Litigation and Legislation Reform in Taiwan Over a 30-Year Period

International Journal of General Medicine, 2021
Ming-Ta Hsieh,1– 3 Li-Hui Lu,2 Chi-Wei Lin,1,4 Yun-Wen Chen5 1Department of Family Medicine and Community Medicine, E-Da Hospital, Kaohsiung City, Taiwan; 2College of Law, National University of Kaohsiung, Kaohsiung City, Taiwan; 3Department of ...
Hsieh MT, Lu LH, Lin CW, Chen YW
doaj  

Understanding bio‐based polymers: A study of origins, properties, biodegradation and their impact on health and the environment

FEBS Open Bio, EarlyView.
This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc, Blaž Stres, Mirica Karlovits, Igor Karlovits, Petra Jerič, Ondrej Panák, Anja Verbič, Blaž Likozar, Uroš Novak   +8 more
wiley   +1 more source

Network Localization of Fatigue in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Fatigue is among the most common symptoms and one of the main factors determining the quality of life in multiple sclerosis (MS). However, the neurobiological mechanisms underlying fatigue are not fully understood. Here we studied lesion locations and their connections in individuals with MS, aiming to identify brain networks ...
Olli Likitalo, Jaakko Kungshamn, Albert Bellmunt‐Gil, Silvia Tommasin, Abhineet Ojha, Matias Viitala, Juho Aaltonen, Jyrki Lötjönen, Juha Koikkalainen, Pauli Ylikotila, Patrizia Pantano, Merja Soilu‐Hänninen, Juho Joutsa   +12 more
wiley   +1 more source

Pharmacists’ clinical knowledge and practice in the safe use of contraceptives: real knowledge vs. self-perception and the implications

BMC Medical Education, 2021
Background Pharmacists are often the first healthcare professionals that patients contact with their illnesses and requests for medical information, which is enhanced following the recent COVID-19 pandemic. Community pharmacists are expected and required
Ana Golić Jelić, Ljiljana Tasić, Ranko Škrbić, Valentina Marinković, Svjetlana Stoisavljević Šatara, Nataša Stojaković, Vanda Marković Peković, Brian Godman   +7 more
doaj   +1 more source

Labour rights of the rare diseases population ‒ breaking the glass ceiling [PDF]

Stanovništvo, 2020
This paper aims to introduce a legal framework for exercising one of the most basic socio-economic rights of people with rare diseases: the right to decent work.
Stojković-Zlatanović Sanja, Sjeničić Marta, Sovilj Ranko   +2 more
doaj   +1 more source

Confidentiality and treatment of young adults : proposals for amendments : the Gillick Proposition [PDF]

, 2015
The law does not determine between legal competency and actual competency of minors in medical issues. The objective of this paper is to put forward proposals to amend the legislation to redefine legal competency on the base that understanding should
Mangion, Ann Marie
core