Results 251 to 260 of about 277,188 (302)

LiraSearch-ultrafast ligand shape and electrostatic matching server. [PDF]

Bioinform Adv
Montalvão RW, Bray S, Veríssimo-Alves M, Cubero E, Grüning B, Pinheiro VB.   +5 more
europepmc   +1 more source

In Vivo Microplastic Detection With Photoacoustic Imaging

Advanced Science, EarlyView.
ABSTRACT Microplastics are posing an escalating threat to both ecological systems and human health. Yet, current methods for investigating their bioaccumulation are highly invasive, requiring destructive analysis of ex vivo tissues via mass spectrometry, dye labelling, or Raman microspectroscopy.
Joseph C. Bear, Olumide Ogunlade, Jayvian Mavi, Emily J. Deniszczyc, Daolong Chen, Heeva Javaheri, Paul Beard, Mark F. Lythgoe, Daniel J. Stuckey, P. Stephen Patrick   +9 more
wiley   +1 more source

Constructing and characterizing trillion-scale combinatorial chemical library. [PDF]

J Cheminform
Su J, Song FV, Huang D, Liao M.
europepmc   +1 more source

GATA4‐Driven Transcription of HtrA1 Promotes Cellular Senescence in Ménière's Disease and Age‐Related Audio‐Vestibular Dysfunction

Advanced Science, EarlyView.
This study identifies the HDAC6/GATA4/HtrA1 axis as a critical driver of cellular senescence in the inner ear. GATA4 nuclear translocation, facilitated by HDAC6 downregulation, transcriptionally activates HtrA1, promoting hair cell senescence, SASP, and audio‐vestibular dysfunction in models of Ménière's disease and age‐related audio‐vestibular ...
Na Zhang, Na Li, Yan Wang, Jing Zhang, Jiahui Liu, Lei Chen, Yongdong Song, Yurong Mu, Yuechen Han, Yafeng Lyu, Xiaofei Li, Hanyue Wang, Jing Wang, Yao Lu, Zhaomin Fan, Daogong Zhang, Haibo Wang   +16 more
wiley   +1 more source

Multisite Assessment of Methods for Cell Preservation Upstream of Single-Cell RNA Sequencing. [PDF]

J Biomol Tech
Kolling Iv FW, Podnar JW, Wilkins O, Fraser CJ, MacDonald ML, Polson SW, Hebert ZT, Chittur SV, Hayden A, Kuentzel M, Heinz M, Huerta GM, Stevenson HS, Karmakar A, Fronick C, Cook L, Vargas S, Xuei X, McGuire P, Zeller M, Zhang Y, Dai R, Wang X, Wai CM, Thimmapuram J, Arora D, Mesa T, Fan J, Alekseyev YO, Cervone F, Williams C, Gorham N, Lemenze A, Goodwin S, Preall J, Whittaker CA.   +35 more
europepmc   +1 more source

Natural Products Inspired Scaffold Diversification Leads to Unnatural Molecular Warhead and Covalent Strategy to Modulating Protein Function through Electrophilic Bromine Transfer

Advanced Science, EarlyView.
We report a new thiolate‐reactive α,α‐gem‐dibromo lactam warhead that activates transcription factor Nrf2 and demonstrates anti‐inflammatory activities, which have implications in cancer, neurodegeneration, and cardiovascular diseases. RNA‐seq illuminated detailed transcriptional profiles, and chemical reactions with cysteine‐containing compounds ...
Beau R. Brummel, Sofia Kokkaliari, Qiwen Gao, Jinjing Chen, Larissa Costa de Almeida, Srinivasarao Tenneti, Derek A. Leas, Eli Levit, Lewis S. Alexander, Khalil A. Abboud, Pingrong Wei, Michael D. Cameron, James R. Rocca, Ranjala Ratnayake, Donna D. Zhang, Hendrik Luesch, Robert W. Huigens III   +16 more
wiley   +1 more source

Rethinking Goods and Services Tax (GST) and Academic Research in India. [PDF]

Cureus
Kandi V.
europepmc   +1 more source

High-depth RNA-seq data to investigate gene regulation mediated by phase-variable DNA methyltransferases in serogroup B <i>Neisseria meningitidis</i>. [PDF]

Microbiol Resour Announc
Ascari A, Blakeway LV, Jennings MP, Seib KL.   +3 more
europepmc   +1 more source

Guide to sound teeth: a syllabus-informed instructional session to provide targeted insights into the history of dentistry. [PDF]

J Med Libr Assoc
Hollister JR, Mages K, Murphy T, Kit-Wells MDC.   +3 more
europepmc   +1 more source

Libraries - Planning and Management in a Time of Change 1

, 2012
Yeadon, Janice, Howard, Susan
core