Results 81 to 90 of about 5,369,083 (302)

Germline TP53 Mutations Causing Diamond–Blackfan Anemia: A French Report

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Diamond–Blackfan anemia is a rare congenital erythroblastopenia typically caused by mutations in ribosomal protein genes. Recently, gain‐of‐function mutations in TP53 have been identified as a novel cause of Diamond–Blackfan anemia. We report two French patients who both harbored a heterozygous TP53 deletion (NM_000546.5: c.1077delA; p ...
Rafael Moisan   +6 more
wiley   +1 more source

What influences chronic pain management? A best–worst scaling experiment with final year medical students and general practitioners [PDF]

open access: yes, 2019
Background: Chronic pain education is an essential determinant for optimal chronic pain management. Given that attitudes and preferences are involved in making treatment decisions, identifying which factors are most influential to final year medical ...
Fowler, Christopher J   +3 more
core   +1 more source

轻型急性缺血性卒中患者院内神经功能恶化预测模型的开发与验证研究 Development and Validation of a Prediction Model of In-Hospital Neurological Deterioration for Patients with Minor Acute Ischemic Stroke

open access: yesZhongguo cuzhong zazhi
摘要: 目的 开发轻型急性缺血性卒中(acute ischemic stroke,AIS)患者院内神经功能恶化的预测模型,为AIS的院内分层管理提供科学依据。 方法 选取中国国家卒中登记Ⅲ(China national stoke registry Ⅲ,CNSR Ⅲ)中发病24 h内的轻型AIS(NIHSS评分≤5分)且未接受rt-PA静脉溶栓或血管内治疗的患者作为研究对象。开发队列为CNSR Ⅲ 2015—2016年入组的2256例患者,验证队列为CNSR Ⅲ 2017 ...
伊珞1*,姜英玉2*,孟霞2,姜勇2,王拥军1,2,谷鸿秋2(*第一作者)
doaj   +1 more source

C-REACTIVE PROTEIN EVALUATION OF MEDICALLY TREATED CASES OF PYOMETRA IN DOGS [PDF]

open access: yesJournal of Veterinary and Animal Sciences, 2019
The potential of biomarkers as diagnostic or prognostic tool in canine pyometra is under investigation. The CRP evaluation of pyometra-affected dogs revealed very high levels (128.51 ± 4.07 to 136.64 ± 6.77 μg/mL) on the day of admission.
M.P. Unnikrishnan   +5 more
doaj  

Prevalência de verdadeiras crises hipertensivas e adequação da conduta médica em pacientes atendidos em um pronto-socorro geral com pressão arterial elevada Prevalence of true hypertensive crises and appropriateness of the medical management in patients with high blood pressure seen in a general emergency room

open access: yesArquivos Brasileiros de Cardiologia, 2008
FUNDAMENTO: Pressão arterial elevada é motivo freqüente de procura por pronto-socorro, sendo possível que muitos pacientes recebam erroneamente um diagnóstico de crise hipertensiva e, conseqüentemente, um tratamento inapropriado.
Francisco das Chagas Monteiro Júnior   +9 more
doaj   +1 more source

Shuttle OFT medical report: Summary of medical results from STS-1, STS-2, STS-3, and STS-4 [PDF]

open access: yes
The medical operations for the orbital test flights which includes a review of the health of the crews before, during, and immediately after the four shuttle orbital flights are reported. Health evaluation, health stabilization program, medical training,
Johnson, P. C., Jr.   +2 more
core   +1 more source

‘They Need to Hear You Say It’: Healthcare Professionals’ Perspectives on Barriers and Enablers to End‐of‐Life Discussions With Adolescents and Young Adults With Cancer

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT End‐of‐life conversations with adolescents and young adults (AYAs) with cancer rarely occur without the guidance of healthcare professionals. As a part of the ‘Difficult Discussions’ study, focused on palliative care and advance care planning discussions with AYAs with cancer, we investigated the factors that healthcare professionals identify ...
Justine Lee   +9 more
wiley   +1 more source

Feasibility and Safety of High‐Dose Proton Re‐Irradiation in Recurrent Pediatric Central Nervous System Tumors: A Single‐Institution Retrospective Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Pediatric central nervous system (CNS) tumors often recur despite multimodality therapy. Although re‐irradiation (re‐RT) has historically been limited by concerns for severe late toxicities, modern techniques have renewed interest in this approach. Proton therapy provides dosimetric advantages that may enable curative re‐treatment with
Jin‐Ho Song   +15 more
wiley   +1 more source

The emergency management of a rape case in a nutshell: adolescent and adult cases

open access: yesSouth African Family Practice, 2017
The management of a rape case in the emergency department is shrouded in an unacceptable level of lack of confidence. Since South Africa has a high incidence of rape, the contribution of health practitioners in addressing the crime successfully is ...
J M Kotzé, H Brits
doaj   +1 more source

Confronting the opioid crisis: Practical pain management and strategies: AOA 2018 critical issues symposium [PDF]

open access: yes, 2019
The United States is in the midst of an opioid crisis. Clinicians have been part of the problem because of overprescribing of narcotics for perioperative pain management.
Hsu, Joseph R   +4 more
core   +1 more source

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