Results 171 to 180 of about 4,969,065 (299)

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

Comparison of post-discharge mortality and medical expenditures in COVID-19 patients according to mechanical ventilation and extracorporeal membrane oxygenation use: The LIFE study. [PDF]

PLoS One
Kawabata J, Goto K, Maeda M, Fukuda H.
europepmc   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

The problem is escalating: Barriers faced by medical students in conducting research; A scoping literature review. [PDF]

PLoS One
Mokhwelepa LW, Sumbane GO, Baloyi S, Risenga S, Malete T.   +4 more
europepmc   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

An Old Icelandic Medical Manuscript.

Annals of medical history
Reprinted from vol. IX, no. 1, p. 60-73 Annals of medical history. ; "References": p. 72-73. ; Mode of access: Internet.
openaire   +1 more source

Reduced Hospital Incidence of Autoimmune Encephalitis During the COVID-19 Pandemic. [PDF]

Neurol Neuroimmunol Neuroinflamm
Wickel J, Chung HY, Konen FF, Rössling R, Bertolini A, Kraft A, Siebenbrodt K, Bittner S, Juranek A, Brokbals M, Räuber S, Klausewitz J, Pfeffer LK, Scherag A, Menge T, Finke A, Doppler K, Urbanek C, Bien CG, Seifert-Held T, Hoffmann F, Wandinger KP, Tauber SC, Süße M, Lewerenz J, Madlener M, Rostasy K, Prüss H, Sühs KW, Kümpfel T, Thaler FS, Leypoldt F, Geis C, GENERATE study group.   +33 more
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Changes in U.S. medical school conflict of interest policies from 2014 to 2023. [PDF]

PLoS One
Bhat S, Shenoy DA, Wojtara M, Kainrath A, Sonfist O, Faulkner J, Wang B, Wilson L, Anderson TS.   +8 more
europepmc   +1 more source