Results 61 to 70 of about 4,200,228 (359)

CYP4X1/sEH‐Dependent Endocannabinoid Metabolism Drives Fibroblast‐Mediated Immunosuppression to Limit Immunotherapy in Colon Cancer

Advanced Science, EarlyView.
A proposed mechanism to explain the role of CYP4X1/sEH‐14,15‐EET‐EA system in colon cancer immune escape. 14,15‐EET‐EA, 14,15‐epoxyeicosatrienoic acid‐ethanolamide; sEH, soluble epoxide hydrolase; CYP4X1, cytochrome P450 4X1; GPR119, G‐protein coupled receptor 119; EGFR, epidermal growth factor receptor; Gs, Gαs subunit; cAMP, cyclic adenosine ...
Min Mo, Xuewei Chen, Yanzhuo Liu, Chenlong Wang, Xuehan Chen, Nan Zhang, Nan He, Ying Li, Jingyi Wang, Honglei Chen, Jing Yang   +10 more
wiley   +1 more source

The Genetic Wiring of Plant Trichomes: From Initiation to Fate Specification

Advanced Science, EarlyView.
Plant trichomes are not just simple hairs but metabolic powerhouses shaped by complex genetic programs. While the MYB‐bHLH‐WD40 module is well studied in Arabidopsis, recent findings reveal that HD‐Zip IV transcription factors drive multicellular and glandular trichome development through dose‐dependent mechanisms.
Meng Li, Yuanbo Huang, Yadi Du, Shuang Wu   +3 more
wiley   +1 more source

Patterns of Marijuana Use and Health Impact: A Survey Among Older Coloradans

Gerontology and Geriatric Medicine, 2019
Access to recreational and medical marijuana is common in the United States, particularly in states with legalized use. Here, we describe patterns of recreational and medical marijuana use and self-reported health among older persons using a ...
Hillary D. Lum MD, PhD, Kanika Arora PhD, J. Alton Croker MA, Sara H. Qualls PhD, Melissa Schuchman MA, Julie Bobitt PhD, Gary Milavetz PharmD, Brian Kaskie PhD   +7 more
doaj   +1 more source

Medical Marijuana-Induced Tacrolimus Toxicity. [PDF]

, 2019
As both recreational and therapeutic marijuana use increases in the US, more attention is being paid to its direct medical and psychoactive effects. One crucial dimension is the potential for marijuana or marijuana-derived therapies to interact with ...
Chism, Keira, Moadel, Daniel
core   +1 more source

“I never realized how hard recovery is.” A quasi‐experimental evaluation of a youth participatory action research project for opioid prevention

American Journal of Community Psychology, EarlyView.
Abstract Youth participatory action research (YPAR) has been effectively used for substance use prevention. Yet, YPAR has not been evaluated for opioids, which negatively impact individuals and communities across the United States. The current study evaluated an opioid‐focused YPAR project.
Elizabeth H. Weybright, Katherine Hampilos, Alison J. White, Cassandra Grinstead, Jennifer Fees, Melanie Greer, Erica L. Doering, Laurie M. Graham   +7 more
wiley   +1 more source

The effect of medical marijuana laws on crime: evidence from state panel data, 1990-2006. [PDF]

PLoS ONE, 2014
Debate has surrounded the legalization of marijuana for medical purposes for decades. Some have argued medical marijuana legalization (MML) poses a threat to public health and safety, perhaps also affecting crime rates. In recent years, some U.S.
Robert G Morris, Michael TenEyck, J C Barnes, Tomislav V Kovandzic   +3 more
doaj   +1 more source

Proceedings of the 2022 Cannabis Clinical Outcomes Research Conference

Medical Cannabis and Cannabinoids, 2022
The Consortium for Medical Marijuana Clinical Outcomes Research, a multi-university collaboration established by the state of Florida in the USA, hosted its second annual Cannabis Clinical Outcomes Research Conference (CCORC) in May 2022.
Nicole E. Smolinski, Ruba Sajdeya, Robert Cook, Yan Wang, Almut G. Winterstein, Amie Goodin   +5 more
doaj   +1 more source

Youth Marijuana and Prescription Drug Abuse in Anchorage [PDF]

, 2016
Complete issue of Alaska Justice Forum 33(1), Spring 2016 at https://scholarworks.alaska.edu/handle/11122/6883.This article examines results of the Adult Perceptions of Anchorage Youth: 2015 Survey (APAYS) to examine perceptions and concerns of Anchorage
Lepage, Cory R., Rivera, Marny
core  

Neuroprotective Effect of Cannabidiol Against Rotenone in Hippocampal Neuron Culture

Chemistry – An Asian Journal, EarlyView.
(–)‐Cannabidiol (CBD) protects primary hippocampal neurons from rotenone, a mitochondrial complex I inhibitor that causes cell death. CBD preserves neuronal viability and morphology, with antagonist assays showing that transient receptor potential vanilloid 1 (TRPV1) mediates this neuroprotective effect.
Seoin Yang, Hyunwoo Choi, Jungnam Kim, Insung S. Choi   +3 more
wiley   +1 more source

Knowledge, Attitude and Practices Regarding Marijuana usage among Medical Students: A Descriptive Cross-sectional Study [PDF]

Journal of Clinical and Diagnostic Research
Introduction: The increment in marijuana use across the world is concerning and needs to be addressed. There has been a cultural change regarding the perception and use of marijuana medicinally and recreationally, even among medical students.
Bhushan Mhetre, Preetika Baghel, Mihir Kshirsagar, Hrishikesh Solunke, Aayushi Goel, Sanaa Gore Datar   +5 more
doaj   +1 more source