Results 161 to 170 of about 1,231,536 (373)

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan, Elizabeth Thomas, Mehari M. Weldemariam, Puranik Purushottamachar, Weiliang Huang, Maureen A. Kane, Yuji Zhang, Nicholas Ambulos, Bi‐Dar Wang, David Weber, Vincent C. O. Njar   +10 more
wiley   +1 more source

The association of diabetes mellitus and routinely collected patient‐reported outcomes in patients with cancer. A real‐world cohort study

Cancer Medicine
Objective Current studies have indicated that diabetes mellitus (DM) is highly prevalent in patients with cancer, but there is little research on consequences on the well‐being of patients during cancer treatment. This analysis evaluates the relationship
Dominik J. Ose, Emmanuel Adediran, Bayarmaa Mark, Krista Ocier, William A. Dunson JR, Cindy Turner, Belinda Taylor, Kim Svoboda, Andrew R. Post, Jennifer Leiser, Howard Colman, Cornelia M. Ulrich, Mia Hashibe   +12 more
doaj   +1 more source

Elucidating prognostic significance of purine metabolism in colorectal cancer through integrating data from transcriptomic, immunohistochemical, and single‐cell RNA sequencing analysis

Molecular Oncology, EarlyView.
Low expression of five purine metabolism‐related genes (ADSL, APRT, ADCY3, NME3, NME6) was correlated with poor survival in colorectal cancer. Immunohistochemistry analysis showed that low NME3 (early stage) and low ADSL/NME6 (late stage) levels were associated with high risk.
Sungyeon Kim, Myunghee Kang, Soyeon Jeong, Jisup Kim, Kyoung Oh Kim, Won‐Suk Lee, Jeong‐Heum Baek, Jung Ho Kim, Seungyoon Nam   +8 more
wiley   +1 more source

Data harvesting vs data farming: A study of the importance of variation vs sample size in deep learning-based auto-segmentation for breast cancer patients [PDF]

arXiv
The aim of this study was to investigate the difference in output, when training a model in three different scenarios: a large clinical delineated data set (with 700/78 patients for training/testing, from the Danish Breast Cancer Group (DBCG) RT Nation Study), a clinical but curated dataset (with 328/36 patients for training/testing, from the DBCG RT ...
arxiv  

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

Molecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka, Tatsuo Nakagawa, Yusuke Ono, Yoshio Kamura, Takeshi Ishida, Hidemasa Kawabata, Kenji Takahashi, Hiroki Sato, Andrew S. Liss, Yusuke Mizukami, Takahide Yokoi   +10 more
wiley   +1 more source

Medical Oncology Group of Australia Annual Scientific Meeting, August 2-4, 2023. [PDF]

Lancet Reg Health West Pac, 2023
Caga-Meller J.
europepmc   +1 more source

Ambulatorial consultation of brazilian nursing oncology - an integrative review

Online Brazilian Journal of Nursing, 2009
The content of the national scientific publications was analyzed quantitatively in the period 2000 to 2007, in databases BIREME, BDENF, LILACS has handled the consultation in oncology nursing review by the method of integration.
Míria Conceição Lavinas Santos, Francisco Stélio Sousa, Mariza Silva Oliveira, Anna Paula Sousa Silva, Izabel Cristina Falcão Juvenal Barbosa, Ana Fátima Carvalho Fernandes   +5 more
doaj  

The emergence of radiation oncology as a distinct medical specialty

, 1985
Philip Rubin
openalex   +1 more source

The effectiveness of a computer-assisted instruction programme on communication skills of medical specialists in oncology [PDF]

, 2002
Robert L. Hulsman, Wynand J.G. Ros, J.A.M. Winnubst, Jozien M. Bensing   +3 more
openalex   +1 more source

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

Molecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu, Jianchao Wang, Fuqing Chen, Xuefeng Wang, Bin Lan, Ruyi Fu, Hong Wen, Fangfang Chen, Wei Hong, Tian‐Yu Tang, Ying He, Gang Chen, Jianyin Zhou, Hai‐Long Piao, Di Chen, Shu‐Yong Lin   +15 more
wiley   +1 more source