CINs of the cytoplasm: dissecting dsRNA signaling in chromosomal instability
Micronuclei, formed during cell division in chromosomal instability settings, rupture and lead to the accumulation of immunogenic double‐stranded RNA in the cytoplasm, activating MAVS‐dependent interferon signaling and innate antitumor immunity.
Aglaia Skolariki+2 more
wiley +1 more source
Medical oncology workload, workforce census, and needs in Spain: two nationwide studies by the Spanish Society of medical oncology. [PDF]
Fernandez Montes A+6 more
europepmc +1 more source
Medical Group Management Association Assembly of Oncology Hematology Administrators … Who Are We? Why Are We Here? [PDF]
John E. Hennessy
openalex +1 more source
TRPM8 levels determine tumor vulnerability to channel agonists
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo+18 more
wiley +1 more source
Update on the management of older patients with pancreatic adenocarcinoma: a perspective from medical oncology. [PDF]
Guillot Morales M+8 more
europepmc +1 more source
Neuro-Oncology. The Essentials. Second Edition. 2007. By Mark Bernstein, Mitchel S. Berger. Published by Thieme Medical Publishers. 496 pages. Price C$170. [PDF]
D. Fulton
openalex +1 more source
Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte+10 more
wiley +1 more source
Levels of evidence and grades of recommendation supporting European society for medical oncology clinical practice guidelines. [PDF]
Skelin M+7 more
europepmc +1 more source
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song+11 more
wiley +1 more source
Extravasation associated with cancer drug therapy: multidisciplinary guideline of the Japanese Society of Cancer Nursing, Japanese Society of Medical Oncology, and Japanese Society of Pharmaceutical Oncology. [PDF]
Matsumoto K+13 more
europepmc +1 more source