Results 121 to 130 of about 7,890,226 (262)

Protocol for quantifying miRNA trafficking across the endosomal membrane

open access: yesFEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh   +2 more
wiley   +1 more source

The use of thermal diffusivity to quantify tissue perfusion

open access: yes, 1981
Thesis (Ph.D.)--Harvard-Massachusetts Institute of Technology Division of Health Sciences and Technology Program in Medical Engineering and Medical Physics, 1981.MICROFICHE COPY AVAILABLE IN ARCHIVES AND SCIENCEVita.Includes bibliographical references.by
Valvano, Jonathan Walker
core  

Corrigendum: Artificial Intelligence for Monte Carlo Simulation in Medical Physics

open access: yesFrontiers in Physics, 2021
David Sarrut   +5 more
doaj   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

open access: yesFEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain   +11 more
wiley   +1 more source

Respiratory fluid mechanics and heat transfer

open access: yes, 1984
Thesis (Ph.D.)--Harvard-Massachusetts Institute of Technology, Division of Health Sciences and Technology, Program in Medical Engineering and Medical Physics, 1984.MICROFICHE COPY AVAILABLE IN ARCHIVES AND SCIENCE.Includes bibliographical references.by ...
Ingenito, Edward Patrick
core  

The role of calcium in the destruction of target cells by cytotoxic T cells [PDF]

open access: yes, 1987
Thesis (Ph. D.)--Massachusetts Institute of Technology, Harvard-MIT Divison of Health Sciences and Technology Program in Medical Engineering and Medical Physics, 1987.Title as it appears in M.I.T.
Allbritton, Nancy L. (Nancy Lynn)
core  

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

open access: yesFEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen   +8 more
wiley   +1 more source

Quantum computing in medical physics

open access: yes
Development of quantum hardware and software is progressing rapidly. With the availability of firstgenerally-accessible quantum computers, their potential use for applications can increasingly beexplored.
Lorenz, Jeanette Miriam
core   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

open access: yesFEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata   +3 more
wiley   +1 more source

Manifesto for medical research [PDF]

open access: yes, 2015
The MRCG want to ensure there is a dynamic medical research environment in Ireland. Ensuring priority investment for medical research will help to deliver patient care, public health service transformation and economic and enterprise development.
Medical Research Charities Group
core  

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