Results 171 to 180 of about 235,273 (262)

Correction: Ibrahim et al. Thiophenes-Naturally Occurring Plant Metabolites: Biological Activities and In Silico Evaluation of Their Potential as Cathepsin D Inhibitors. <i>Plants</i> 2022, <i>11</i>, 539. [PDF]

Plants (Basel)
Ibrahim SRM, Omar AM, Bagalagel AA, Diri RM, Noor AO, Almasri DM, Mohamed SGA, Mohamed GA.   +7 more
europepmc   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Plant-Derived Heterocyclic Compounds: A Promising Review on Natural Remedies for Rheumatoid Arthritis Management and Their Mechanistic Insights in Inflammation and Joint Protection. [PDF]

Basic Clin Pharmacol Toxicol
Dai J, Xia X, Hu X, Kanagaraj T, Rajalakshmi K, Deshpande M, Kiruthiga N, Zhu D, Fan Y.   +8 more
europepmc   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Constitutive Expression of AtVTE2 in Flax Is Associated with Changes in Isoprenoid Metabolism and Stem Cell-Wall Composition. [PDF]

Int J Mol Sci
Hasiewicz-Derkacz K, Zalewski I, Boba A, Dymińska L, Lysh D, Czuj T, Prescha A, Skórkowska-Telichowska K, Szopa J, Kulma A.   +9 more
europepmc   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Comparative Effects of High-Molecular-Weight Chitosan and Chitosan Oligosaccharide Lactate on Metabolic Adjustment and Salinity Tolerance in <i>Cucumis sativus</i> L. [PDF]

Molecules
Hawrylak-Nowak B, Stasińska-Jakubas M, Sawicki J, Matraszek-Gawron R, Jarmulska W, Czelej-Wrzesień M, Dresler S.   +6 more
europepmc   +1 more source

[Melilotus--medical plants].

Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 2005
openaire   +1 more source

Importance of the Tomato as such as medical plant

International Journal of Advanced Research in Biological Sciences (IJARBS), 2017
Hamid kheyrodin, Sadaf kheyrodin
openaire   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source