Results 81 to 90 of about 235,273 (262)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Antitumor Effects of Juncus effusus L. subsp. effusus in a Mammary Tumor Model: Regulation of ERα, p53, PCNA, and HIF-1α

open access: yesMolecules
Estrogen receptor-positive breast cancer remains difficult to treat, driving the search for new therapeutic agents. Juncus effusus L., a medicinal plant rich in bioactive constituents, has shown preliminary anticancer activity, yet its efficacy in ...
İrem Ergin   +6 more
doaj   +1 more source

Inhibitory effect of Thymus vulgaris extract on memory impairment induced by scopolamine in rat

open access: yesAsian Pacific Journal of Tropical Biomedicine, 2015
Objective: To investigate the effect of Thymus vulgaris (T. vulgaris) on learning and memory functions in scopolamine-induced memory deficit in rats. Memory enhancing activity in scopolamine-induced amnesic rats was investigated by assessing the Morris ...
Zahra Rabiei   +5 more
doaj   +1 more source

UZBEKSITAN REGION OF MEDICAL PLANTS

open access: yes, 2023
This article discusses medicinal plants in the treatment of ...
openaire   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Antibiofilm activity and phytochemical compounds of Selaginella plana extract against human pathogenic microorganisms

open access: yesNotulae Scientia Biologicae
Selaginella plana (Desv.) Heiron, traditionally used in Indonesia, is known for its efficacy in treating infections in open wounds. Untreated wounds can lead to infections, cellulitis, sepsis, and biofilm formation, all of which may delay the wound ...
Juen Carla Warella   +3 more
doaj   +1 more source

Effects of hydroalcoholic extract of Borago officinalis on naloxone-precipitated withdrawal syndrome in morphine-dependent mice

open access: yesBangladesh Journal of Pharmacology, 2016
The aim of the present study was to investigate the effect of hydroalcoholic extract of Borago officinalis on morphine withdrawal syndrome in mice. Morphine-dependent group received morphine for nine days and then received naloxone via intraperitoneal ...
Zahra Rabiei   +2 more
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

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