Results 91 to 100 of about 386,873 (310)

Improving Awareness of Colon Cancer Screening in the Homeless Population of Burlington, Vermont [PDF]

open access: yes, 2018
Homeless populations are significantly less likely to access preventative cancer screening, yet this is a major cause of morbidity and mortality in this population.
Nadeau, Alexis
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Search Process Checklist [PDF]

open access: yes, 2018
The Search Process Checklist is a tool that is used in instructional sessions with nurses in reference to evidence-based practice and literature searching. It is intended as a reference handout. It is under a creative commons license. If you would like a
Brown, Roy E.
core   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

The International Conference on Intelligent Biology and Medicine (ICIBM) 2018: bioinformatics towards translational applications

open access: yesBMC Bioinformatics, 2018
The 2018 International Conference on Intelligent Biology and Medicine (ICIBM 2018) was held on June 10–12, 2018, in Los Angeles, California, USA. The conference consisted of a total of eleven scientific sessions, four tutorials, one poster session, four ...
Xiaoming Liu   +6 more
doaj   +1 more source

Developing Comprehensive Diabetes Education Materials for Structured Patient Education Programs in Primary Care Setting [PDF]

open access: yes, 2016
Diabetes education is a key factor for a successful diabetes care. Comprehensive diabetes education materials for conducting structured diabetes education programs were rarely found in primary care setting in Indonesia.
Agrimon, O. H. (Oryzati)   +1 more
core  

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Publication Rates of Oculoplastic Surgery and Orbit Abstracts Presented at Turkish Ophthalmological Association National Congresses: 10-Year Analysis

open access: yesTürk Oftalmoloji Dergisi
Objectives: This study aimed to examine the publication rates of abstracts related to oculoplastic surgery and orbital diseases presented at the Turkish Ophthalmological Association National Congresses (TOA-NCs) in 2013-2022.
Yusuf İkbal Erdoğdu, Nilay Yüksel
doaj   +1 more source

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