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The Regulation (EU) 2019/6 establishes that the veterinary prescriptions should follow a cascade, according to their availability of the market. In sum, the veterinarian is authorized to use a medicine for human use only if there is no product available
Rafaela Nogueira+7 more
doaj +1 more source
Real‐World Comparison of High‐Efficacy Versus Non‐High‐Efficacy Therapies in Multiple Sclerosis
ABSTRACT Objective The choice of the first disease modifying treatment (DMT) in multiple sclerosis (MS) is a topic of great interest, and whether high‐efficacy DMTs should be the first choice remains debated. We compared treatment outcomes (no evidence of disease activity [NEDA] and its components) between treatment‐naïve relapsing–remitting MS (RRMS ...
Sarmad Al‐Araji+9 more
wiley +1 more source
Physician-prescribed museum visit benefits on mental health: results of an experimental study
BackgroundArt and cultural activities have been associated with health benefits. The effects of a physician-prescribed museum visit on the mental health of patients remain to unclear.
Olivier Beauchet+8 more
doaj +1 more source
Medicare Prescription Drugs: Medical Necessity Meets Fiscal Insanity [PDF]
Medicare is facing severe financial strains that threaten its future viability. On a per capita basis, Medicare spending is increasing at twice the rate of the gross domestic product, and, according to Medicare's chief actuary, the program is facing a ...
Jagadeesh Gokhale, Joseph Antos
core
ABSTRACT Objective To evaluate the long‐term impact of early intensive treatment (EIT) versus escalation (ESC) strategies using high‐efficacy disease‐modifying therapies (HE‐DMTs) on disability progression in relapsing multiple sclerosis (RMS). Methods This observational study included 4878 RMS patients from the Italian Multiple Sclerosis Register ...
Pietro Iaffaldano+47 more
wiley +1 more source
Objectives Antibiotic resistance is a major public health concern and is greatly exacerbated by inappropriate antibiotic use at a community level.
M. Zapata-Cachafeiro+6 more
semanticscholar +1 more source
Durable B‐Cell Impairment While Sparing IgA B Cells After Ocrelizumab Therapy in Multiple Sclerosis
ABSTRACT Objectives Ocrelizumab (OCR), a humanized anti‐CD20 monoclonal antibody, is highly efficient in relapsing–remitting multiple sclerosis (RR‐MS). We assessed early cellular B‐cell profiles in patients prior to OCR treatment, on OCR treatment, and after 15 months of therapy discontinuation.
Alexandra Garcia+20 more
wiley +1 more source
Adolescence represents a vulnerable time for the development of both drug use/abuse and mental illness. Although previous research has substantiated a relationship between drug use and suicidal behavior, little research has examined this relationship ...
A. Divin, K. Zullig
semanticscholar +1 more source
Automedicación en inmigrantes latinoamericanos adultos de Sevilla [PDF]
OBJECTIVE: To estimate the prevalence of non-prescription pharmaceutical use in the Latin American immigrant population. METHOD: A descriptive, cross-sectional study of a representative sample of 190 immigrants.
González López, José Rafael+2 more
core +3 more sources
The Road Not Taken: Misclassifying an Anti‐Seizure Medication as a Failure
ABSTRACT Objective To quantify how often anti‐seizure medications (ASMs) appear ineffective yet provide benefit when considering seizure frequency (SF) variability. Methods We used the CHOCOLATES seizure diary simulator to generate 100,000 patient seizure diaries that reflect natural SF variation in a heterogeneous population.
Christopher N. Henry+1 more
wiley +1 more source