Results 111 to 120 of about 5,853,445 (350)

ODM-DQA-Reporter: A Generic Approach to Assess and Monitor Basic Data Quality of Medical Research Data in Operational Data Model (ODM) Format [PDF]

open access: hybrid, 2022
Ayşenur Süer   +6 more
openalex   +1 more source

Recommended Core Measures for Evaluating the Patient-Centered Medical Home: Cost, Utilization, and Clinical Quality [PDF]

open access: yes, 2012
Outlines the process of the Patient-Centered Medical Home Evaluators' Collaborative for identifying core standardized measures and their recommended principles and measures for evaluating cost and utilization and clinical ...
Asaf Bitton   +2 more
core  

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Correlation analysis between single disease quality management and efficiency indicators of a tertiary hospital in China

open access: yesBMC Health Services Research
Background In the framework of continuous improvement of medical quality, specific (single) disease management has become a key priority. However, the current research on the correlation of various items for single disease management and efficiency ...
Shuxiang Lan   +4 more
doaj   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

Innovative Medicaid Initiatives to Improve Service Delivery and Quality of Care: A Look at Five State Initiatives [PDF]

open access: yes, 2011
Outlines initiatives in Alabama, Oklahoma, Oregon, Pennsylvania, and Washington to implement patient-centered medical home models designed to coordinate and improve quality of care; strategies; key lessons; and new opportunities under healthcare ...
Juliana Macri   +3 more
core  

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Factors affecting the number of nonconformities from the assessment of safety in medical laboratory according to ISO 15190:2003

open access: yesJournal of Associated Medical Sciences, 2016
Background: Bureau of Laboratory Quality Standards established medical laboratory safety accreditation program according to ISO 15190: 2003 in Thailand since May 2013. Nonconformities (NCs) were found from 1 to 18 in each laboratory. Number of NCs may be
Surasak Muenphon   +8 more
doaj  

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