Results 81 to 90 of about 17,847,497 (340)
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
脑梗死医疗质量控制指标修订历程 Revision Process of Medical Quality Control Indicators in Cerebral Infarction
Zhongguo cuzhong zazhi中国脑梗死医疗质量控制指标于2008年制定，分别于2012年、2015年、2018年和2020年进行了多次修订。该指标体系是我国开展脑梗死医疗质量监测和评估的标准，是脑梗死医疗质量持续改进的反馈工具，在医疗质量控制与管理工作中发挥着重要作用。 Abstract: The medical quality control indicators in cerebral infarction were developed in 2008 and revised in 2012, 2015, 2018, and
YANG Xin1,2, LI Zixiao1,2,3, WANG Yongjun1,2,3
doaj +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Zhongguo cuzhong zazhi运动神经元病（motor neuron disease，MND）是一组神经变性疾病，肌萎缩侧索硬化（amyotrophic lateral sclerosis，ALS）是其主要类型。目前ALS/MND缺乏特效诊疗手段，患者预后差。 ALS/MND虽然较罕见，但目前我国该系列疾病住院患者有快速增长趋势，结合我国实际情况，存在ALS/MND临床医疗质量控制的迫切需求。国家神经系统疾病医疗质量控制中心于2022年设立了MND质控专病组，启动了ALS/MND临床医疗质量控制体系建设。以 ...
HE Ji, FAN Dongsheng
doaj +1 more source
BMC Health Services Research, 2023 Background Affordability and accessibility of hospital care are under pressure. Research on hospital care financing focuses primarily on incentives in the financial system outside the hospital.
L. V. L. van Leeuwen +3 more
doaj +1 more source
Community Care of North Carolina: Putting Health Reform Ideas Into Practice in Medicaid [PDF]
, 2009 Summarizes assessments of how an enhanced medical home model of care that involves local nonprofit community networks and emphasizes care coordination, disease and care management, and quality improvement has affected cost savings and quality of ...
Samantha Artiga
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, 2018 Uncertainty estimation methods are expected to improve the understanding and quality of computer-assisted methods used in medical applications (e.g., neurosurgical interventions, radiotherapy planning), where automated medical image segmentation is ...
Blatti-Moreno, Marcela +6 more
core +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Clinical pathway for diagnosis and treatment of new diagnosed multiple myeloma in Guangxi
Guangxi Yike Daxue xuebaoMultiple myeloma, an incurable clonal plasma cell dysplasia, is the second most common hematological malignancy. Standardized diagnosis and treatment are crucial for prolonging the survival of myeloma patients and improving the quality of their lives ...
The Control Center of Medical Quality of Guangxi Hematology +1 more
doaj +1 more source
Closing the Divide: How Medical Homes Promote Equity in Health Care [PDF]
, 2007 Presents findings from the Commonwealth Fund 2006 Health Care Quality Survey, and demonstrates how having stable insurance, a regular provider and, in particular, a medical home, improves health care access and quality among vulnerable ...
Anne C. Beal +4 more
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