Results 21 to 30 of about 1,049,894 (308)

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

Disasters and its Effects on Medical Records Department; a Case Report. The Importance of Protection of Patient Information from Flood Damages

مدیریت اطلاعات سلامت, 2010
Introduction: Disasters whether natural or man-made can inflict widespread damage in every society. Disaster effects on hospitals were discussed by many specialties in many fields.
Azar Kabirzadeh, Benyamin Mohsenisaravi, Aghdas Kabirzadeh   +2 more
doaj  

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source

Constraining Factors of Research from the Viewpoint of Faculty Members of Zahedan University of Medical Sciences

مدیریت اطلاعات سلامت, 2010
Introduction: After human resource training, Research is a basis of cultural, social and economical expansion and university is the main basis of research system.
Afsaneh Karimi, Yosef Mehdipour, Ali Mohammadpour, Samira Pirozanfar   +3 more
doaj  

Effects of HBsAg carriers on pregnancy complications in pregnant women: a retrospective cohort study

Frontiers in Medicine, 2023
ObjectiveHepatitis B virus (HBV) infection is a major health threat worldwide, especially in developing countries. We aimed to investigate the impact of hepatitis B carrier on pregnancy complications in pregnant women, in China.MethodsThis retrospective ...
Mengqing Weng, Jie Wang, Jie Wang, Jingfeng Yin, Wenning Ren, Caiping Wei, Wenshan Yang, Huimin He   +7 more
doaj   +1 more source

Time, the final frontier

Molecular Oncology, EarlyView.
This article advocates integrating temporal dynamics into cancer research. Rather than relying on static snapshots, researchers should increasingly consider adopting dynamic methods—such as live imaging, temporal omics, and liquid biopsies—to track how tumors evolve over time.
Gautier Follain, Michal Dibus, Omkar Joshi, Guillaume Jacquemet   +3 more
wiley   +1 more source

A Comparative Study of the Iran Ministry of Health Patient and Family Education Standards with Joint Commission on Accreditation of Healthcare Organizations

مدیریت اطلاعات سلامت, 2010
Introduction: According to role of patient and family education in the process of patient care, Joint Commission on Accreditation of Healthcare Organizations (JCAHO) has considered the patient and family education standards in the hospital accreditation ...
Ali Mohammadpor, Yosef Mehdipour, Afsaneh Karimi, Ali Rahdari   +3 more
doaj  

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

Molecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu, Ning Ding, Xiaobo Xu, Yedan Chen, Yong Zhang, Jingwen Liu, Jiebai Zhou, Hairong Bao, Donghui Zhang, Yijun Song, Yang Shao, Yuanlin Song   +11 more
wiley   +1 more source

A Survey on the Satisfaction Rate of Users about the Quality of Hospital Information System in Hospitals Associated with Kermanshah University of Medical Sciences

مدیریت اطلاعات سلامت, 2011
• Introduction: Hospital information system (HIS) is a computerized system which is used as an electronic tool for patient information management and plays a significant role in providing quality health care services.
Amir abbas Azizi, Shahla Safari, Ali Mohammadi, Jalal Kheirollahi, Mahdie Shojaei Baghini   +4 more
doaj  

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

Molecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova, Dominika Maurencova, Barbora Salovska, Marek Kratky, Tomas Mracek, Zuzana Korandova, Alena Pecinova, Pavla Vasicova, David Rysanek, Ladislav Andera, Ivo Fabrik, Rudolf Kupcik, Pavel Kashmel, Pinky Sultana, Vojtech Tambor, Jiri Bartek, Josef Novak, Marie Vajrychova, Zdenek Hodny   +18 more
wiley   +1 more source