Results 151 to 160 of about 7,953,956 (301)

Review of Medical Audit [PDF]

open access: yesJournal of the Royal Society of Medicine, 1990
openaire   +2 more sources

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

کاربرد مدارک و اطلاعات پزشکی در تحقیقات از دیدگاه پژوهشگران

open access: yesمدیریت اطلاعات سلامت, 2008
مقدمه: امروزه تحقیقات در علوم مختلف به عنوان ابزاری قدرتمند و شایان توجه جهت ارزیابی آخرین دستاوردهای علمی به كار می‌رود. مهم‌ترین ابزار راه‌گشای محققین در علوم پزشکی برای انجام تحقیقات، مدارك و اطلاعات پزشكی بیماران در بایگانی‌های بیمارستان‌ها می‌باشد ...
Sima Ajami, Faeze Kalbasi, Mahnaz Kabiri
doaj  

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

Medical review licensing outcomes in drivers with visual field loss in Victoria, Australia. [PDF]

open access: yesClin Exp Optom, 2016
Muir C   +9 more
europepmc   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

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