Results 101 to 110 of about 3,654,618 (260)

The burden of group A Streptococcus (GAS) infections: The challenge continues in the twenty-first century

open access: yesiScience
Summary: Streptococcus pyogenes is a Gram-positive bacterium, also known as Group A Streptococcus (GAS), that has become a significant threat to the healthcare system, infecting more than 18 million people and resulting in more than 500,000 deaths ...
Aswin Thacharodi   +7 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Evaluation of Some Aspects of Educational Inputs and Outputs of Community Medicine Departments in Iran Medical Sciences Schools and Universities [PDF]

open access: yesStrides in Development of Medical Education, 2007
Background: Human health is strongly related to economic political cultural administrative and environmental conditions Therefore Medical sciences are not limited to biomedical sciences but also include social and psychological sciences This viewpoint ...
Saadat Torabian   +2 more
doaj  

A bibliometric study of scientific output in Tabriz University of Medical Science 1988-1996 [PDF]

open access: yes, 2005
A bibliometrics analysis was recruited to visualize the scientific output of faculty members of Tabriz University of Medical Sciences for a period of eight years (1988-1996) .The subject fields surveyed are: Hygiene and Nutrition, Nursing and Midwifery ...
Biglu, Mohammad-Hossein, Omid, Askari
core  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Carbapenem-resistant Acinetobacter baumannii raises global alarm for new antibiotic regimens

open access: yesiScience
Summary: Carbapenem-resistant Acinetobacter baumannii (CRAB) is a top-priority pathogen causing a nosocomial infection that increases morbidity and mortality.
Aswin Thacharodi   +4 more
doaj   +1 more source

A View of Healthscience --Based on the investigation of the current situation in Germany-- [PDF]

open access: yes, 1986
We examined the current situation of studies on health in Germany, especially medical anthropology by v. Weizsacker and v. Gebsattel, medical sociology, social medicine and general medicine in the faculties of medicine of German universities and the new ...
石井, 誠士
core  

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

A radiogenomic clinical decision support system to inform individualized treatment in advanced nasopharyngeal carcinoma

open access: yesiScience
Summary: Both concurrent chemoradiotherapy (CCRT) and induction chemotherapy (ICT) followed by CCRT are standard care of advanced nasopharyngeal carcinoma (NPC). However, tailoring personalized treatment is lacking.
Xue-Liang Fang   +18 more
doaj   +1 more source

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