Results 151 to 160 of about 3,677,242 (302)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Medicine and Medical Science

Journal of Japan Academy of Nursing Science, 2000
openaire   +2 more sources

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Correction: Global mapping of sexually transmitted Chlamydia trachomatis disease: a systematic review and meta-analysis. [PDF]

BMC Infect Dis
Sameni F, Hajiarab T, Bayat S, Ahmadi M, van Belkum A, Dadashi A, Goudarzi M, Dadashi M.   +7 more
europepmc   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Evaluation of large language models in medical examinations: A scoping review protocol. [PDF]

PLoS One
Wang W, Wang B, Zhu Y, Wang Z, Peng S.
europepmc   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Different SARS-CoV-2 Subvariants and Coagulation Markers Trend: A Retrospective Multicentric Study From Iranian Network for Research in Viral Diseases (INRVD). [PDF]

Health Sci Rep
Razavi A, Koltapeh MP, Nazari T, Morvaridi A, Banivaheb B, Saeb S, Moulaeian M, Zakaryaei A, Sabzalian A, Raei M, Razavi B, Motlaghzadeh S, Hosseini SS, Karami H, Ghafari P, Aboofazeli A, Nastarvand S, Sarabi NKN, Avakian A, Ebadinejad S, Keyhani T, Danafar P, Rahimlou R, Heidarian S, Mondeali M, Nafe-Monfared F, Jafarpour M, Samiee M, Birang F, Mirzazadeh A, Abadi SAF, Barkhordari K, Siavoshi S, Biklari M, Khodabakhsh M, Javadi A, Mirzaee S, Didgar F, Etebari M, Soltanmohamad S, Shahbaz B, Kord E, Shahri SMH, Ebrahimzade M, Moghaddam AA, Sanavi FS, Moattari A, Edalat F, Sheijani MF, Moghadami M, Yaghubi T, Mojtahedi A, Heidarzadeh A, Naghipour M, Luyeh MS, Nazemi P, Alipasandi K, Albaji M, Afzali M, Shokouhi N, Ezani A, Najari HR, Hosseini M, Ghobadi A, Momeni A, Fattahi SZ, Mohsenzadeh M, Jafari M, Azizi A, Pouryousef S, Tabarraei A, Moradi A, Azimi S, Yahyapour Y, Bayani M, Poortahmasebi V, Varshochi M, Ziaee M, Ghafari S, Javanmard D, Soleimani A, Mozhgani SH, Mokhames Z, Akhoundimeybodi Z, Astani A, Abdollahi A, Hadadi A, Salehi MR, Hajiabdolbaghi M, Raeeskarami SR, Kafan S, Montazeri M, Pazoki M, Riahi T, Talebi-Taher M, Ataei-Pirkooh A, Bokharaei-Salim F, Faiz SHR, Kalantari S, Yasin Z, Jazayeri SM.   +100 more
europepmc   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Correction: Prevalence of cigarette and e-cigarette dual use and associated factors among people who smoke in China aged 20-69 years. [PDF]

BMC Public Health
Xie Y, Li Y, Su Z, Liu Z, Cui Z, Huang Z, Cheng A, Zhou X, Li J, Qin R, Liu Y, Xia X, Song Q, Zhao L, Xiao D, Wang C.   +15 more
europepmc   +1 more source