Results 191 to 200 of about 3,654,618 (260)

Correction: Integrative analysis of serum lipids and chronic gastritis: causal insights from mendelian randomization and experimental models. [PDF]

Lipids Health Dis
Chu X, Biao Y, Li H, Chen J, Yin J, Gao X, Wang S, Ma J, Yi L, Zhang Y, Zhang M, Liu Z.   +11 more
europepmc   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Correction: Seroprevalence and Determinants of Hepatitis B Virus and Hepatitis C Virus Infection Among Pregnant Women in North India: A Cross-Sectional Study. [PDF]

Cureus
Yadav A, Agarwal M, Agarwal V, Jain A, Rungta S, Mishra P, Goel A, Agarwal A, Reddy H, Yadav P, Wardhan M, Gupta NK, Pathak M.   +12 more
europepmc   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

APECx-Anaesthesia, Perfusion and Surgical Practices in Cardiac Surgery: Main Study Protocol of a Modular Multiphase Prospective International Multicentre Observational Study. [PDF]

Acta Anaesthesiol Scand
Seegers JC, Grewal N, van Vliet R, Berger T, Bhatia B, Cozowicz C, Czerny M, D'Andria Ursoleo J, Corte AD, Dodic S, Fanning JP, Gasteiger L, Grewal S, Grønlykke L, Huhn R, Idhrees M, Itenov TS, Jassar AS, Ju JW, Karalapillai D, Kunst G, Lannemyr L, Lin DY, Mariani C, Martinsson A, McCabe E, Milne B, Monaco F, Møller-Sørensen PH, Neuner M, Pacini D, Perry LA, Raman J, Schmidt AF, Schoenhoff F, Segal R, Neto AS, Shook DC, Torregroza C, Vives M, Zochios V, van Meenen DMP, Beukers AM.   +42 more
europepmc   +1 more source

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

Molecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek, Jenny Sprooten, Abhishek D. Garg   +2 more
wiley   +1 more source

Aligning action across major infectious diseases in a dynamic global health landscape. [PDF]

PLOS Glob Public Health
Ford N, Kasaeva T.
europepmc   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Correction: MMP-3 cleavage of Lamin A induces pro-migratory nuclear deformity, nucleophagy, and their autophagic secretion with extracellular vesicles in metastatic cancer. [PDF]

Cell Commun Signal
Eguchi T, Taha EA, Nakano K, Tiwari V, Takebe K, Inoue T, Xing L, Sogawa C, Okamoto K, Calderwood SK.   +9 more
europepmc   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source