Results 81 to 90 of about 3,654,618 (260)

Health behaviour among Lithuanian adult population, 2006 [PDF]

, 2007
Book describes data on national 25-64 year lithuanians health behaviour survey starting from 1994 every other year. Book would be useful for people who work in scientific research in social health, medical, social science area, health policy formating ...
Grabauskas, Vilius, Klumbiene, Jurate, Kriaucioniene, Vilma, Paalanen, Laura, Petkeviciene, Janina, Prättälä, Ritva, Sakyte, Edita   +6 more
core   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Interview with Millicent Goldschmidt [PDF]

, 2017
An oral history interview with Millicent Goldschmidt about her career at University of Texas Health Science Center at Houston (UTHealth) where she has held faculty positions in the Department of Diagnostic and Biomedical Sciences at UTHealth School of ...
Goldscmidt, Millicent, Ph.D.
core   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

The relationship between metabolic syndrome and environmental endocrine disruptors: A systematic review and meta-analysis

iScience
Summary: Metabolic syndrome (MetS) is considered to be an important factor leading to an increased risk of chronic non-communicable diseases. Studies have found that exposure to environmental endocrine disruptors (EEDs) is associated with MetS, but the ...
Kai Pan, Jie Xu, Feng Li, Ahmad Zaharin Aris, Huawen Yu, Yuzhu Xu, Jie He, Chengxing Wang, Jie Yu   +8 more
doaj   +1 more source

Evaluation of the Utility of Online Objective Structured Clinical Examination Conducted During the COVID-19 Pandemic

Advances in Medical Education and Practice, 2022
Mona Arekat,1 Mohamed Hany Shehata,2,3 Abdelhalim Deifalla,4,5 Ahmed Al-Ansari,6 Archana Kumar,6 Mohamed Alsenbesy,1,7 Hamdi Alshenawi,8 Amgad El-Agroudy,1 Mariwan Husni,9,10 Diaa Rizk,11 Abdelaziz Elamin,12 Afif Ben Salah,2 Hani Atwa6,13 1Internal ...
Arekat M, Shehata MH, Deifalla A, Al-Ansari A, Kumar A, Alsenbesy M, Alshenawi H, El-Agroudy A, Husni M, Rizk D, Elamin A, Ben Salah A, Atwa H   +12 more
doaj  

Clinical significance of mild inferolateral wall ischemia of the left ventricle on 99mTc-MIBI myocardial perfusion single photon emission computed tomography (SPECT) [PDF]

, 2013
INTRODUCTION: Mild ischemia in the inferolateral wall on myocardial perfusion imaging is seen frequently in practice. The aim of this study is to assess the importance of the above issue on myocardial perfusion SPECT with coronary angiography ...
ABBASZADEH, M, ABDI-ARDEKANI, A, AMINI, A, ASSADI, M, ASSADI, M, JAVADI3, H, NABIPOUR, I, POURBEHI, M   +7 more
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Cross-sectional analyses of metabolites across biological samples mediating dietary acid load and chronic kidney disease

iScience
Summary: Chronic kidney disease (CKD) is a major public health burden, with dietary acid load (DAL) and gut microbiota playing crucial roles. As DAL can affect the host metabolome, potentially via the gut microbiota, we cross-sectionally investigated the
Ilias Attaye, Beverley Beynon-Cobb, Panayiotis Louca, Ana Nogal, Alessia Visconti, Francesca Tettamanzi, Kari Wong, Gregory Michellotti, Tim D. Spector, Mario Falchi, Jordana T. Bell, Cristina Menni   +11 more
doaj   +1 more source