Results 171 to 180 of about 10,264,567 (303)

Real-Time SpO₂ Estimation from Chest Reflectance Photoplethysmography: Algorithm Development and Clinical Validation Against Arterial SaO₂. [PDF]

Sensors (Basel)
Lee W, Shin J, Song M, Song MK, Kim KM, Noh GJ, Cho S.   +6 more
europepmc   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Amplification-free colorimetric detection of exosomal miRNA using a CRISPR/Cas13a-activated HRP/Au/MoS₂ nanobiohybrid catalyst. [PDF]

Nano Converg
Lee MJ, Shin M, Lim J, Ahn HR, Jung D, Liu S, Li C, Choi JH, Choi JW.   +8 more
europepmc   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Engineered Allosteric Biosensor for In Situ DNA Glycosylase Detection in Neuroblastoma Risk Stratification and Drug Resistance Monitoring. [PDF]

Adv Sci (Weinh)
Lu Y, Zhang Y, Zhang X, Zhang M, Zhang F, Sun J, Yang Y, Liu K, Wang P, Luo S, Zhang W.   +10 more
europepmc   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Human cardiac measurements with diamond magnetometers. [PDF]

Sci Adv
Omar M, Benke M, Zhang S, Zhang J, Wang Y, Kuebler M, Sharbati P, Rahimpour A, Gück A, Kapitonova M, Kadam D, René Izquierdo Geiser C, Haller J, Trautmann A, Jag-Lauber K, Rölver R, Nguyen TD, Gizzi L, Schweizer M, Abdelsayed M, Wickenbrock I, Edmonds AM, Markham M, Koss PA, Schnell O, Hofmann UG, Ball T, Beck J, Budker D, Wrachtrup J, Wickenbrock A.   +30 more
europepmc   +1 more source

Medical Center grounds diagram

This glass lantern slide features a black and white diagram of the Medical College of South Carolina Medical Center ...
Medical College of South Carolina (1952-1969). Department of Medical Illustration
core  

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

The Terminator-A Blood Test for Early Detection of 50 Cancers. [PDF]

Public Health Chall
Sium AF, Lucero-Prisno DE.
europepmc   +1 more source