Results 231 to 240 of about 10,088,500 (301)

A Low-Cost Wearable Multimodal Brain Signal Acquisition System Integrating EEG and fNIRS for Depression Detection. [PDF]

Biosensors (Basel)
Fei Z, Li H, Ying Z, Li X, Zhang Y, Zhao Q, Lian B, Cai W, Cui J, Yu T, Zhao X, Lv S, Yu Z, Ding G, Ying Y, Zhu Y.   +15 more
europepmc   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

Multi-frequency asynchronous optical coherence elastography by direct demodulation. [PDF]

Biomed Opt Express
Schmidt G, McAuley R, Bouma BE, Uribe-Patarroyo N.   +3 more
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Enhancing compressed sensing and parallel imaging accelerated magnetic resonance angiography using a dual-domain projection generative adversarial network. [PDF]

Med Phys
Xu L, Bian Y, Gan K, Pan B, Yeom KW, Moseley M, Yang Q, Gong NJ.   +7 more
europepmc   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Reconfigurable optical arithmetic logic unit and its applications. [PDF]

Nat Commun
Zhou X, Yuan M, Xiao H, Jiang Y, Zhang P, Tian Y.   +5 more
europepmc   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Cross-Modality Deep Learning Denoising for Low-Dose μSPECT: Transfer of PET-Trained U‑Net and Diffusion Models

Chemical & Biomedical Imaging
Elise Taragola, Sara Neyt, Boxiao Yu, Maya Abi Akl, Boris Vervenne, Kuang Gong, Stefaan Vandenberghe, Christian Vanhove, Florence M. Muller   +8 more
doaj   +1 more source

A protocol for assessing virtual and mixed reality environments with real-time electromyographic (EMG) biofeedback during upper limb physical exercises. [PDF]

MethodsX
Haggag MT, Awad MI, Elbokl AM, Abdullah BA.   +3 more
europepmc   +1 more source