Results 121 to 130 of about 1,644,666 (282)

CD168 Identifies Proliferating Pancreatic Islet Cells in Murine and Human

open access: yesAdvanced Science, EarlyView.
This study identifies CD168 as a conserved surface marker for proliferating β‐cells in mouse, human islets, and pancreatic islet tumors. CD168⁺ cells show high proliferation and low insulin expression. CD168+ cells form mostly uni‐β lineage clones, and some of the clones are multi‐lineage.
Shubo Yuan   +21 more
wiley   +1 more source

Versatile CRISPR‐Cas Tools for Gene Regulation in Zebrafish via an Enhanced Q Binary System

open access: yesAdvanced Science, EarlyView.
This study introduces CRISPR‐Q, a transgenic CRISPR‐Cas system leveraging the QFvpr/QUAS binary expression platform in zebrafish. CRISPR‐Q overcomes previous challenges in achieving stable and efficient gene regulation. By enabling precise spatiotemporal control of transcript knockdown (CRISPR‐QKD) and gene activation (CRISPR‐Qa), it provides a ...
Miaoyuan Shi   +13 more
wiley   +1 more source

Hospital Industry Restructuring and Input Substitutability: Evidence from a Sample of Italian Hospitals [PDF]

open access: yes
In this paper we investigate the economic rationality of the bed downsizing process characterising the hospital industry worldwide in the last decades, providing new evidence on the factor substitutability in the production of hospital services.
Davide Vannoni   +2 more
core  

Dr. John H. Gibbon, Jr. and Jefferson\u27s Heart-Lung Machine: Commemoration of the World\u27s First Successful Bypass Surgery [PDF]

open access: yes, 2015
On May 6, 1953 at Jefferson Medical College Hospital, Dr. John Heysham Gibbon, Jr., his staff, and with the help of his latest-designed heart-lung machine, “Model II,” closed a very serious septal defect between the upper chambers of the heart of ...
Angelo, F. Michael
core   +1 more source

rWTC‐MBTA Vaccine, Alone and Enhanced with Anti‐PD1, Elicits Immune Responses against CNS and Peripheral B‐Cell Lymphoma

open access: yesAdvanced Science, EarlyView.
An autologous whole‐tumor‐cell vaccine (rWTC‐MBTA) is evaluated in murine CNS lymphoma. Subcutaneous vaccination activates dendritic cells, broadens T‐cell priming, and drives lymphocyte trafficking to brain tumors, producing durable tumor control. Longitudinal bioluminescence and adoptive‐transfer assays verify CNS engagement. Combination with anti‐PD‐
Yaping Zhang   +10 more
wiley   +1 more source

Medical Staff of Swedish Methodist Hospital

open access: yesYonsei Medical Journal, 2021
Sung Ku Ahn   +4 more
openaire   +2 more sources

Analisis Faktor Kontribusi Risiko Klinis Terjadinya Adverse Outcome di Igd Rs Xtahun 2006 [PDF]

open access: yes, 2008
Background: The function of the emergency department is toserve medical emergency patient as high clinical risk areas.The lack identification of care delivery problems in emergencydepartment could be disadvantages to the patient, medicalstaff, and ...
Raharjo, S. (Saptono)
core  

The Mitochondrial Guardian α‐Amyrin Mitigates Alzheimer's Disease Pathology via Modulation of the DLK‐SARM1‐ULK1 Axis

open access: yesAdvanced Science, EarlyView.
Dietary habits play a key role in chronic diseases, and higher annual consumption of fruit and vegetable may lower risk of dementia. Artificial intelligence predicts the lipid‐like compound α‐Amyrin (αA) from plants with edible peels as a drug candidate against Alzheimer's disease.
Shu‐Qin Cao   +36 more
wiley   +1 more source

Kinerja Pegawai Rumah Sakit Umum Daerah Bengkalis (Studi Kasus Pelayanan Pasien yang Dirujuk ke RSUD Arifin Ahmad Pekanbaru) [PDF]

open access: yes, 2016
The research present describe about quality of staff in Bengkalis Hospital (study case service of patient to Arifin Ahmad Hospital Pekanabru). Hospital are public place for in healthy.
Maulana, M. A. (Muhammad)   +1 more
core  

Palmitoylation‐Mediated Ubiquitination of SRPK1 Regulates Ferroptosis in High‐Fat‐Induced Erectile Dysfunction

open access: yesAdvanced Science, EarlyView.
Elevated exogenous palmitic acid promotes the S‐palmitoylation of SRPK1 in endothelial cells, a dynamic process governed by ZDHHC24 and APT1. This post‐translational modification strengthens the interaction between SRPK1 and the E3 ubiquitin ligase MIB1, thereby facilitating the proteasomal degradation of SRPK1.
Xiao‐Hui Tan   +11 more
wiley   +1 more source

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