Results 51 to 60 of about 1,049,028 (260)

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Iran Military Health Network: An Optimal Governance Approach [PDF]

open access: yesJournal of Evidence Based Health Policy, Management & Economics
Health is considered a fundamental right for every individual, which is essential for enjoying critical aspects of life such as quality of life, productivity, life expectancy, happiness, life satisfaction, social interactions, and well-being.
Mohammadreza Sheikhy-Chaman   +3 more
doaj  

Automatic Work-Hours Recorder for Medical Staff (Staff Hours): Mobile App Development

open access: yesJMIR mHealth and uHealth, 2020
BackgroundThere are numerous mobile apps for tracking work hours, but only a few of them record work hours automatically instead of relying on manual logging.
Chiang, Ting-Wei   +3 more
doaj   +1 more source

Network Localization of Fatigue in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Fatigue is among the most common symptoms and one of the main factors determining the quality of life in multiple sclerosis (MS). However, the neurobiological mechanisms underlying fatigue are not fully understood. Here we studied lesion locations and their connections in individuals with MS, aiming to identify brain networks ...
Olli Likitalo   +12 more
wiley   +1 more source

Needle Stick Injury and Hepatitis B Virus Vaccination Status of Medical Staff in Tertiary Care Hospitals of Islamabad and Rawalpindi

open access: yesPakistan Journal of Medical Research
Objective: To ascertain the vaccination coverage against Hepatitis B virus (HBV) and to identify the most vulnerable group for needle stick injury and HBV infection among healthcare workers of tertiary care hospitals of Islamabad and Rawalpindi. Study
Muhammad Aslam Shaikh   +5 more
doaj   +2 more sources

Factors correlating to decisions for prescribing pharmacological treatment and referrals in suspected peripheral neuropathy cases in chat consultation-based application

open access: yesHeliyon
Introduction: Since the COVID-19 pandemic, there has been increasing use ofchat-based telemedicine, including for patients with neuropathy complaints. It is imperative to learn how to effectively use telemedicine. This study describes the characteristics
Pukovisa Prawiroharjo   +10 more
doaj   +1 more source

Will Memantine Exacerbate Seizures in People With Epilepsy? A Prospective Cohort Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate whether add‐on memantine would exacerbate seizures in people with epilepsy. Methods This was a prospective cohort study. People with epilepsy diagnosed with cognitive impairment were consecutively invited. Those who agreed were followed up for at least 24 weeks.
Peiyu Wang   +7 more
wiley   +1 more source

Reduced Muscular Carnosine in Proximal Myotonic Myopathy—A Pilot 1H‐MRS Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Myotonic dystrophy type 2 (proximal myotonic myopathy, PROMM) is a progressive multisystem disorder with muscular symptoms (proximal weakness, pain, myotonia) and systemic manifestations such as diabetes mellitus, cataracts, and cardiac arrhythmias.
Alexander Gussew   +11 more
wiley   +1 more source

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