Heart failure with preserved ejection fraction (HFpEF) accounts for half of the heart failure cases. It is characterised by microvascular dysfunction, associated with reduced pericyte coverage and diminished STAT3 expression in pericytes. Loss of STAT3 impairs pericyte adhesion, promotes senescence, and activates a pro‐fibrotic gene program.
Leah Rebecca Vanicek+15 more
wiley +1 more source
Redesign of web-based exam for knowledge evaluation in Advanced Mathematics for pharmaceutical students based on analysis of the results [PDF]
The usage of the information technologies everywhere leads to demands for new manners of education. Modern e-learning environments lead the teaching, the learning and the evaluation of acquired knowledge and skills of the students to a new era. The students' motivation for e-learning is considered.
arxiv
A Content Analysis of Interviewee Reports of Medical School Admissions Interviews [PDF]
Introduction. Prospective medical school applicants use Internet websites to gain information about medical school interviews as well as to offer their experience in such interviews.
Altmaier , PhD, Elizabeth M.+2 more
core +1 more source
Ion channel function of polycystin‐2/polycystin‐1 heteromer revealed by structure‐guided mutagenesis
Mutations in polycystin‐1 (PC1) or polycystin‐2 (PC2) cause autosomal‐dominant polycystic kidney disease (ADPKD). We generated a novel gain‐of‐function PC2/PC1 heteromeric ion channel by mutating pore‐blocking residues. Moreover, we demonstrated that PC2 will preferentially assemble with PC1 to form heteromeric complexes when PC1 is co‐expressed ...
Tobias Staudner+7 more
wiley +1 more source
Family Centered Rounds Simulation and Medical Students\u27 Perceptions [PDF]
Background: Studies show that family centered rounds (FCR) improve family satisfaction by involving the families in their children’s care. Medical students consistently find FCR beneficial to families but have differing attitudes regarding benefits to ...
Lee, Clifton
core +1 more source
Expressing one’s feelings and listening to others increases emotional intelligence: A pilot study of Asian medical students [PDF]
BackgroundThere has been considerable interest in Emotional Intelligence (EI) in undergraduate medical education, with respect to student selection and admissions, health and well-being and academic performance.
Abe, Keiko+6 more
core +1 more source
Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation
Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley +1 more source
On the shoulders of students? The contribution of PhD students to the advancement of knowledge [PDF]
Using the participation in peer reviewed publications of all doctoral students in Quebec over the 2000-2007 period this paper provides the first large scale analysis of their research effort. It shows that PhD students contribute to about a third of the publication output of the province, with doctoral students in the natural and medical sciences being
arxiv
Ethics and the medical practitioner [PDF]
Historically, the inculcation of good ethical practice within the Maltese medical community has been achieved through a high ethical standard assumed by the teachers which was passed on to their students.
Cauchi, Maurice N.
core
Autophagy in cancer and protein conformational disorders
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley +1 more source