Results 191 to 200 of about 2,267,015 (325)
An Address ON THE PRINCIPLES OF WOUND TREATMENT AS ESTABLISHED BY LISTER AND THE SUBSEQUENT MODIFICATIONS IN TREATMENT: Delivered to the Students' Medical Society, Aberdeen [PDF]
Francis Caird
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Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski+19 more
wiley +1 more source
Medical students' perception of paid E-learning. [PDF]
Mohri P+7 more
europepmc +1 more source
This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau+9 more
wiley +1 more source
How much do medical students know about cancer risk factors? [PDF]
Keten HS, Dogan GG, Akbayram HT, Isik O.
europepmc +1 more source
THE MEDICAL LIBRARY AND THE MEDICAL STUDENT.
E C, Long, P G, Miller
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THE VALUE TO THE MEDICAL STUDENT OF PHYSIOLOGIC STUDY. [PDF]
John Benson
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A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp+13 more
wiley +1 more source