Results 71 to 80 of about 2,267,015 (325)

Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation

open access: yesFEBS Letters, EarlyView.
The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt   +8 more
wiley   +1 more source

Circulating histones as clinical biomarkers in critically ill conditions

open access: yesFEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez   +17 more
wiley   +1 more source

Adverse Childhood Experiences in Medical Students: Implications for Wellness. [PDF]

open access: yes, 2019
ObjectiveThe primary purpose of the study was to assess the prevalence of adverse childhood experiences (ACEs) in a cohort of third-year medical students and characterize their childhood protective factors.MethodsThe authors developed a web-based ...
Griffin, Erin J   +2 more
core  

Expressing one’s feelings and listening to others increases emotional intelligence: A pilot study of Asian medical students [PDF]

open access: yes, 2013
BackgroundThere has been considerable interest in Emotional Intelligence (EI) in undergraduate medical education, with respect to student selection and admissions, health and well-being and academic performance.
Abe, Keiko   +6 more
core   +1 more source

Insights into pegRNA design from editing of the cardiomyopathy‐associated phospholamban R14del mutation

open access: yesFEBS Letters, EarlyView.
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao   +7 more
wiley   +1 more source

Spanish medical students’ attitudes and views towards Mental Health and Psychiatry: a multicentric cross-sectional study. [PDF]

open access: yes, 2014
Objective The aim of this study is to investigate the attitudes towards mental illness and psychiatry among fifth year Spanish medical students. Methods The study included 171 students from three medical schools located in different areas of Spain ...
A Bulbena   +41 more
core   +2 more sources

Family Centered Rounds Simulation and Medical Students\u27 Perceptions [PDF]

open access: yes, 2017
Background: Studies show that family centered rounds (FCR) improve family satisfaction by involving the families in their children’s care. Medical students consistently find FCR beneficial to families but have differing attitudes regarding benefits to ...
Lee, Clifton
core   +1 more source

A Content Analysis of Interviewee Reports of Medical School Admissions Interviews [PDF]

open access: yes, 2003
Introduction. Prospective medical school applicants use Internet websites to gain information about medical school interviews as well as to offer their experience in such interviews.
Altmaier , PhD, Elizabeth M.   +2 more
core   +1 more source

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